Protein Alignment Gbs-70E and Ppp1r3c

DIOPT Version :10

• Sequence 1: NP_648708.2
• Gene: Gbs-70E / 39588
• FlyBaseID: FBgn0036428
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_058550.1
• Gene: Ppp1r3c / 53412
• MGIID: 1858229
• Length: 317
• Species: Mus musculus
• Alignment Length: 206
• Identity: 82/206 - (39%)
• Similarity: 118/206 - (57%)
• Gaps: 23/206 - (11%)

  Fly   140 CICSKDSDSNGEVSRGP----KKHVIFADDEGLSLTEVRVMSE-PSNVPPYWSMKF----LEQIT 195
            |:..|....:....:.|    ||.|:|||.:|||||.:.|.|: |..  |.|.::|    |..|:
Mouse    61 CLSVKQEAKSQSEWKSPHNQAKKRVVFADSKGLSLTAIHVFSDLPEE--PAWDLQFDLLDLNDIS 123

  Fly   196 QGLVSPHPPDQWTVDFKQPASDYLSFRQKIERDFVSLENVIVKDEESIVVGTIKVKNIDFQKEII 260
            ..| ..|.......||.||::||||||.:.:::||.|||..::|.  .|.||:||||:.|:|::.
Mouse   124 SSL-KLHEEKNLVFDFPQPSTDYLSFRDRFQKNFVCLENCSLQDR--TVTGTVKVKNVSFEKKVQ 185

  Fly   261 VRVTWDDWKSQQDIFCTYAR-AYGPATCAHVVFDTFSFKITLP---PSSKRLEFCICYRTNETEY 321
            ||:|:|.||:..|:.|.|.: .|..:..     |||||.|.||   |:.:::||||.|..|...:
Mouse   186 VRITFDTWKTYTDVDCVYMKNVYSSSDS-----DTFSFAIDLPRVIPTEEKIEFCISYHANGRIF 245

  Fly   322 WDNNDGKNYTI 332
            ||||:|:||.|
Mouse   246 WDNNEGQNYRI 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gbs-70E	NP_648708.2	PBD_PPP1R3	<136..198	CDD:455118	22/66 (33%)
		CBM_21	224..332	CDD:427265	47/111 (42%)
Ppp1r3c	NP_058550.1	PBD_PPP1R3C	51..128	CDD:439280	23/69 (33%)
		PP1-binding motif	84..87		1/2 (50%)
		Interaction with EPM2A. /evidence=ECO:0000250|UniProtKB:Q9UQK1	141..263		55/123 (45%)
		CBM_21	151..256	CDD:427265	47/111 (42%)