Protein Alignment Gbs-70E and Ppp1r3c

DIOPT Version :10

• Sequence 1: NP_648708.2
• Gene: Gbs-70E / 39588
• FlyBaseID: FBgn0036428
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001012072.1
• Gene: Ppp1r3c / 309513
• RGDID: 1309132
• Length: 317
• Species: Rattus norvegicus
• Alignment Length: 243
• Identity: 91/243 - (37%)
• Similarity: 126/243 - (51%)
• Gaps: 49/243 - (20%)

  Fly   100 NQPKSCLSRKSCLHKSQNTTASSADLSPTDTDVADSASHSCICSKDSDSNGEVSRGPKKHVIFAD 164
            |:||..   |.||...|...:.....||          ||               ..||.|:|||
  Rat    53 NKPKPL---KPCLSVKQEAKSQKEWKSP----------HS---------------QAKKRVVFAD 89

  Fly   165 DEGLSLTEVRVMSEPSNVP--PYWSMKF----LEQITQGLVSPHPPDQWTVDFKQPASDYLSFRQ 223
            .:|||||.:.|.|:   :|  |.|.::|    |..|:..| ..|.......||.||:|||||||.
  Rat    90 SKGLSLTAIHVFSD---LPEEPAWDLQFDLLDLNDISSSL-KLHEEKNLVFDFPQPSSDYLSFRD 150

  Fly   224 KIERDFVSLENVIVKDEESIVVGTIKVKNIDFQKEIIVRVTWDDWKSQQDIFCTYAR-AYGPATC 287
            :.:::||.|||..::|.  .|.||:||||:.|:|::.||:|:|.||:..|:.|.|.: .||.:..
  Rat   151 RFQKNFVCLENCSLQDR--TVTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKNVYGSSDS 213

  Fly   288 AHVVFDTFSFKITLP---PSSKRLEFCICYRTNETEYWDNNDGKNYTI 332
                 |||||.|.||   |:.:::||||.|..|...:||||:.:||.|
  Rat   214 -----DTFSFAIDLPRVIPTEEKIEFCISYHANGRVFWDNNEAQNYRI 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gbs-70E	NP_648708.2	PBD_PPP1R3	<136..198	CDD:455118	21/67 (31%)
		CBM_21	224..332	CDD:427265	47/111 (42%)
Ppp1r3c	NP_001012072.1	PBD_PPP1R3C	51..128	CDD:439280	31/106 (29%)
		PP1-binding motif	84..87		1/2 (50%)
		Interaction with EPM2A. /evidence=ECO:0000250|UniProtKB:Q9UQK1	141..263		56/123 (46%)
		CBM_21	151..256	CDD:427265	47/111 (42%)