Protein Alignment CG4613 and PROZ

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: XP_054231085.1
• Gene: PROZ / 8858
• HGNCID: 9460
• Length: 470
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 62/277 - (22%)
• Similarity: 107/277 - (38%)
• Gaps: 66/277 - (23%)

  Fly   116 AKAFRV----NRCA---SCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFL-FCGGTLINDRYV 172
            |:.:|:    .:|.   .|.|||....:.....|    ..||..::...... ||||.:|.:.:|
Human   223 AQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQ----DLPWQVKLTNSEGKDFCGGVIIRENFV 283

  Fly   173 LTAAHC--VHGMDMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIP 235
            ||.|.|  :|    |.::|:......|...|.:  .:...|.|:.||..:..:|::||.|:.||.
Human   284 LTTAKCSLLH----RNITVKTYFNRTSQDPLMI--KITHVHVHMRYDADAGENDLSLLELEWPIQ 342

  Fly   236 LVDTMRPACLPSNWLQNFDF--------QKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRAT 292
            ......|.|.|..     ||        .:.:::||  ::.|....:.|....|.::...:|
Human   343 CPGAGLPVCTPEK-----DFAEHLLIPRTRGLLSGW--ARNGTDLGNSLTTRPVTLVEGEEC--- 397

  Fly   293 SYRSMIVDTMMCAGYVKTGGRDACQGDS-------GGPLIVRDR--IFRLAGVVSFGYGCAKPDA 348
               ..:::       |....|..|:..|       .|.::.|:.  .:.|.||:.     ::|..
Human   398 ---GQVLN-------VTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLG-----SQPVG 447

  Fly   349 PGVY----TRVSRYLEW 361
            ...:    |:||||..|
Human   448 GQAHMVLVTKVSRYSLW 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	55/250 (22%)
PROZ	XP_054231085.1	GLA	92..156	CDD:214503
		EGF_CA	<165..193	CDD:238011
		FXa_inhibition	206..235	CDD:464251	2/11 (18%)
		Trypsin	259..>411	CDD:459667	40/177 (23%)