Protein Alignment CG4613 and KLK15

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 88/245 - (35%)
• Similarity: 124/245 - (50%)
• Gaps: 32/245 - (13%)

  Fly   135 NRIVGGTQVRTNKYPW-IAQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVRL----LQL 194
            ::::.|.:...:..|| :|...||.| .||.:||:..:||:||||    ..|.:.|||    |:.
Human    20 DKLLEGDECAPHSQPWQVALYERGRF-NCGASLISPHWVLSAAHC----QSRFMRVRLGEHNLRK 79

  Fly   195 DRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAI 259
            ......|..|..|.   .|..|:..|..:||.||||.||..|...:|||.||:..  ....:..:
Human    80 RDGPEQLRTTSRVI---PHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRC--PHPGEACV 139

  Fly   260 VAGWGL--SQEGGSTSSVLQEVVVP---------IITNAQCRATSYRSMIVDTMMCAGYVKTGGR 313
            |:||||  ..|.|:..|...:|.:|         ||::..| ..||...:.:||:||| .:..|.
Human   140 VSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC-DKSYPGRLTNTMVCAG-AEGRGA 202

  Fly   314 DACQGDSGGPLIVRDRIFRLAGVVSFG-YGCAKPDAPGVYTRVSRYLEWI 362
            ::|:|||||||:...   .|.|:||:| ..|.....|||||:|..|||||
Human   203 ESCEGDSGGPLVCGG---ILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	86/242 (36%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	86/238 (36%)