DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4613 and prss60.2

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	272	Identity:	99/272 - (36%)
Similarity:	143/272 - (52%)	Gaps:	44/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CASCT--------------CG-VPNVNRIVGGTQVRTNKYPWIAQIIRGTF--LFCGGTLINDRY 171
            ||:.|              || .|..:|||||.......:||...:....:  .||||:||:..:
Zfish     6 CATLTLLICVKGSLSQLNVCGQAPLNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFCGGSLISSEW 70

  Fly   172 VLTAAHCVHGMDMRGVSVRLLQLDRS--STHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPI 234
            |||||||:.|:....:.|.|.:..:.  :|| ..:|:||....|..|:..:..:|||||||...:
Zfish    71 VLTAAHCLPGVSESSLVVYLGRRTQQGVNTH-ETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAV 134

  Fly   235 PLVDTMRPACL----------PSNWLQNFDFQKAIVAGWGLSQEGGS--TSSVLQEVVVPIITNA 287
            ...|.:||.||          .|:|          :.|||..|.|.:  ...:|||.::|::.|.
Zfish   135 TFNDYIRPVCLAAQNSVYSAGTSSW----------ITGWGDVQAGVNLPAPGILQETMIPVVAND 189

  Fly   288 QCRATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR-DRIFRLAGVVSFGYGCAKPDAPGV 351
            :|.|......:.:.|:|||..| ||:|.||||||||::.| ..::..||:.|:|||||.|::|||
Zfish   190 RCNAQLGSGTVTNNMICAGLAK-GGKDTCQGDSGGPMVTRLCTVWIQAGITSWGYGCADPNSPGV 253

  Fly   352 YTRVSRYLEWIA 363
            |||||:|..||:
Zfish   254 YTRVSQYQSWIS 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	91/242 (38%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	90/241 (37%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	91/242 (38%)
		Tryp_SPc	34..267	CDD:238113	92/244 (38%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587890
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840