Protein Alignment CG4613 and tmprss2

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001008623.1
• Gene: tmprss2 / 494080
• ZFINID: ZDB-GENE-041212-48
• Length: 486
• Species: Danio rerio
• Alignment Length: 321
• Identity: 116/321 - (36%)
• Similarity: 158/321 - (49%)
• Gaps: 51/321 - (15%)

  Fly    61 VQSD-FIDDLIE------GHK------QQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLE 112
            |.|| |.|:|.:      |:|      |.|||..|...|...|.||.||
Zfish   191 VCSDGFNDNLAKQACAEIGYKDTYSGYQGILSPSLDFISACQSSTAVSL---------------- 239

  Fly   113 GGGAKAFRVNRCASCT-CGVPNVNRIVGGTQVRTNK--YPWIAQIIRGTFLFCGGTLINDRYVLT 174
                         .|| ||....|||||||.| |:|  :||...:.......|||::|...::||
Zfish   240 -------------KCTDCGRSTGNRIVGGTTV-TSKGVWPWQVSLHYSGRHLCGGSIITPYWILT 290

  Fly   175 AAHCVHGM-DMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVD 238
            ||||||.. :..|.:|....|.:|........||.....| .::|.:..:||||:||:..:.:..
Zfish   291 AAHCVHQFSNPGGWTVYAGYLTQSEMASASGNSVNRIVIH-DFNPNTNENDIALMRLNTALTIST 354

  Fly   239 TMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATS-YRSMIVDTM 302
            .:||.|||:..:.....|...|.|||....|||:|:.|||..:.:|.:..|.:.. |..:|.|||
Zfish   355 NIRPVCLPNKGMSFTAQQDCYVTGWGALFSGGSSSATLQEAKIQLIDSTICNSRPVYNGLITDTM 419

  Fly   303 MCAGYVKTGGRDACQGDSGGPLIVRDR-IFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            :|||.: .||.|:|||||||||:...| ::.|.|..|:|.|||..:.||||..|:.:|:||
Zfish   420 ICAGKL-AGGVDSCQGDSGGPLVTNVRSLWWLLGDTSWGDGCAVRNKPGVYGNVTYFLDWI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	90/230 (39%)
tmprss2	NP_001008623.1	DUF3824	<18..>77	CDD:372351
		LDLa	132..168	CDD:238060
		SRCR_2	173..248	CDD:470597	23/85 (27%)
		Tryp_SPc	252..482	CDD:238113	91/231 (39%)