DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4613 and CG11313

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	92/271 - (33%)
Similarity:	130/271 - (47%)	Gaps:	53/271 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 NRIVGGTQVRTNKYPWI---------AQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVR 190
            |:|..|.:....::.|:         .|.:|   .:|.|:|||:|||:||||||      ..:.|
  Fly   114 NQITKGNETVLTEFAWMVLLEYRPHDGQQLR---TYCAGSLINNRYVVTAAHCV------SAATR 169

  Fly   191 LLQLD---RSSTHLGVTRSVAFAHAHVGY---DPVSL------VH----------DIALLRLDQP 233
            ..:.|   |.|..||...:.|......|.   :||.:      :|          ||||:||.:.
  Fly   170 ARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLARE 234

  Fly   234 IPLVDTMRPACLPSN-WLQNFDFQKAI-VAGWG--LSQEGGSTSSVLQEVVVPIITNAQCRATSY 294
            :....::||.||||. .|||:...:|. |||||  |:.|   :|.|..::.|..:....|| ..|
  Fly   235 VAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSE---SSPVKMKLRVTYVEPGLCR-RKY 295

  Fly   295 RSMIV--DTMMCAGYVKTGGRDACQGDSGGPLIV-RDRIFRLAGVVSFGYGCAKPDAPGVYTRVS 356
            .|::|  |:.:||.....|  |:|.|||||||:. .:.::.|.|:||||..|.....|.|||.|.
  Fly   296 ASIVVLGDSHLCAEGRSRG--DSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVYTNVL 358

  Fly   357 RYLEWIAVNTR 367
            .|..||..|.|
  Fly   359 SYETWITQNIR 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	87/263 (33%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	87/262 (33%)
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	89/265 (34%)
		Tryp_SPc	116..364	CDD:214473	87/262 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457384
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940