DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4613 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	92/261 - (35%)
Similarity:	142/261 - (54%)	Gaps:	21/261 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 AKAFRVNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHC-V 179
            :.:|:.:.|...|. .|..:::.||......::||.|.:.:.....||.|||::.:::||||| |
  Rat   167 SSSFKFSGCGRRTI-TPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFV 230

  Fly   180 HGMDMRGVSVR---LLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMR 241
            ...:.:...|.   ||...::.      |:|.....|..|...:..:|||::||..|:...:.:|
  Rat   231 RSANPKDWKVSFGFLLSKPQAQ------RAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIR 289

  Fly   242 PACLP---SNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRA-TSYRSMIVDTM 302
            .||||   ..:..|.|   .:|.|||..:..|.:.::||:..|.||.|..|.: .:|..:|...|
  Rat   290 RACLPEATQKFPPNSD---VVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGM 351

  Fly   303 MCAGYVKTGGRDACQGDSGGPLIVRDR--IFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVN 365
            :|||::: |..|||||||||||:..|.  |:.|||:||:|..||.|:.|||||||:.|.:||:..
  Rat   352 LCAGFLE-GRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSK 415

  Fly   366 T 366
            |
  Rat   416 T 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	85/235 (36%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	85/234 (36%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	85/235 (36%)
		Tryp_SPc	187..415	CDD:238113	87/237 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960