Protein Alignment CG4613 and KLK1

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 79/244 - (32%)
• Similarity: 124/244 - (50%)
• Gaps: 22/244 - (9%)

  Fly   132 PNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCV----------HGMDMRG 186
            |..:|||||.:...:..||.|.:...:...|||.|::.::|||||||:          |.:....
Human    20 PIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 84

  Fly   187 VSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPI-PLVDTMRPACLPSNWL 250
            .:.:.:.:..|..|.|...|:...|.....:..|  ||:.||||.:|. .:.|.::...||:.
Human    85 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYS--HDLMLLRLTEPADTITDAVKVVELPTE-- 145

  Fly   251 QNFDFQKAIVAGWG-LSQEGGSTSSVLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVKTGGRD 314
            :.......:.:||| :..|..|....||.|.:.|:.|.:|: .::...:.|.|:|.|::: ||:|
Human   146 EPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECK-KAHVQKVTDFMLCVGHLE-GGKD 208

  Fly   315 ACQGDSGGPLIVRDRIFRLAGVVSFGY-GCAKPDAPGVYTRVSRYLEWI 362
            .|.|||||||:. |.:  |.||.|:|| .|..|:.|.|..||..|::||
Human   209 TCVGDSGGPLMC-DGV--LQGVTSWGYVPCGTPNKPSVAVRVLSYVKWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	76/238 (32%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	77/239 (32%)