Protein Alignment CG4613 and PRSS41

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 91/291 - (31%)
• Similarity: 131/291 - (45%)
• Gaps: 62/291 - (21%)

  Fly   113 GGGAKAF-------RVNRCASCTCGVPNVNRIV-GGTQVRTNKYPWIAQIIRGTFLFCGGTLIND 169
            |||.:..       :.....|..||...::.:| ||.:....::||.|.:.......|||:|::.
Human    39 GGGREGHFLCPAESQEEELLSEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSR 103

  Fly   170 RYVLTAAHCVH--------------------GMDMRGVSVRLLQLD--RSSTHLGVTRSVAFAHA 212
            |:||:||||..                    ..::|..|.|....|  .:...|||.|
Human   104 RWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLR------- 161

  Fly   213 HVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDF---QKAIVAGWGLSQEGGSTSS 274
                      :|||||||...:.....::|.|:.|:   .|:|   ....|.||||....|:...
Human   162 ----------NDIALLRLASSVTYNAYIQPICIESS---TFNFVHRPDCWVTGWGLISPSGTPLP 213

  Fly   275 V---LQEVVVPIITNAQC----RATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIV-RDRIF 331
            .   |:|..|.|:.|.:|    ...|.||||.|:|.||| .:.|..|.|:|||||||:. :|.::
Human   214 PPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAG-AEDGSVDTCKGDSGGPLVCDKDGLW 277

  Fly   332 RLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            ...|:||:|..|.:|:.|||||.:|.|..||
Human   278 YQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	83/259 (32%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	85/259 (33%)