DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4613 and l(2)k05911

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	122/372 - (32%)
Similarity:	181/372 - (48%)	Gaps:	71/372 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PPSRGYFYPKPERLPPLPVNGSTTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVAS---ETPS 90
            ||:.| .:|     ||||        |.||             .|.........||.|   .||.
  Fly   306 PPTTG-GWP-----PPLP--------THPP-------------NHHYPTHPTTGGVPSTKRTTPR 343

  Fly    91 DTASSLGST----SLSSSASPVF-------PLEGGGAKAFRVNRCASCTCGVPNVNRIVGGTQVR 144
            .|:.:..:|    :..|..|||.       |:.|..::...: :|.:.....|:..|||||....
  Fly   344 PTSPARPTTTRRPTYPSYPSPVTTTTTTRRPVSGTSSEGLPL-QCGNKNPVTPDQERIVGGINAS 407

  Fly   145 TNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRSSTHLG------- 202
            .:::||||.:.:....||||:||.:.::|||||||..|....|:.       .:.|||
  Fly   408 PHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMTSWDVAA-------LTAHLGDYNIGTD 465

  Fly   203 -----VTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACL---PSNWLQNFDFQKAI 259
                 |:|.:.....|.|::..:|.:|:|:|.|.:|:|....::|.||   ||...:::..|.|.
  Fly   466 FEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSPSQQSRSYSGQVAT 530

  Fly   260 VAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATSYRSM---IVDTMMCAGYVKTGGRDACQGDSG 321
            |||||..:|.|...|:||:|.:||.|||:|.....|:.   |:::|:|||   ...:|:|.||||
  Fly   531 VAGWGSLRENGPQPSILQKVDIPIWTNAECARKYGRAAPGGIIESMICAG---QAAKDSCSGDSG 592

  Fly   322 GPLIVRD-RIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTR 367
            ||:::.| ..:...|:||:|.||.|...|||||||:..|.||..|.:
  Fly   593 GPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIYKNIK 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	92/244 (38%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	91/243 (37%)
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	92/244 (38%)
		Tryp_SPc	400..637	CDD:238113	93/246 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	4.010