DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4613 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	278	Identity:	98/278 - (35%)
Similarity:	147/278 - (52%)	Gaps:	43/278 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 KAFRVNRCASCT--------------CGVPNVN-RIVGGTQVRTNKYPWIAQIIRGTF--LFCGG 164
            |.:|:. ||:.|              ||...:| |||||.......:||...:....:  .||||
Zfish     2 KMWRLT-CATLTLLICVKGSLSQLNVCGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYGGHFCGG 65

  Fly   165 TLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRSSTHLGVT-RSVAFAHAHVGYDPVSLVHDIALL 228
            :||:..:|||||||:.|:....:.|.|.:..:...::..| |:||.:..|..|:..:..:|||||
Zfish    66 SLISSEWVLTAAHCLSGVSETTLVVYLGRRTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALL 130

  Fly   229 RLDQPIPLVDTMRPACL----------PSNWLQNFDFQKAIVAGWGLSQEGGS--TSSVLQEVVV 281
            ||...:...:.:||.||          .|:|          :.|||..|.|.:  ...:|||.::
Zfish   131 RLSSAVTFTNYIRPVCLAAQNSVYSAGTSSW----------ITGWGDIQAGVNLPAPGILQETMI 185

  Fly   282 PIITNAQCRATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR-DRIFRLAGVVSFGYGCAK 345
            |::.|.:|.|......:.:.|:|||..: ||:|.||||||||::.| ..::..||:.|:|||||.
Zfish   186 PVVANDRCNALLGSGTVTNNMICAGLTQ-GGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCAD 249

  Fly   346 PDAPGVYTRVSRYLEWIA 363
            |::||||||||:|..||:
Zfish   250 PNSPGVYTRVSQYQSWIS 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	88/241 (37%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	87/240 (36%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	89/243 (37%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587889
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930