DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4613 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	106/314 - (33%)
Similarity:	170/314 - (54%)	Gaps:	22/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 GPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGGAKAFR 120
            |.|..|.||.:  .::..::|...:.:.:....|.|..::|..:        |:..||..:....
  Rat   146 GFPSYVSSDHL--RVDALEEQFQGDFVSINHLLPDDKVTALHHS--------VYMREGCTSGHVV 200

  Fly   121 VNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHGM--- 182
            ..:|::|........|||||......::||...:....:..|||::|...:::||||||:.:
  Rat   201 TLKCSACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHP 265

  Fly   183 DMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPS 247
            ....|.|.|:.|..|.....:...:.:   |..|.|..|.:||||::|.:|:...:|::|.|||
  Rat   266 KSWTVQVGLVSLMDSPVPSHLVEKIIY---HSKYKPKRLGNDIALMKLSEPLTFDETIQPICLP- 326

  Fly   248 NWLQNF-DFQKAIVAGWGLSQEG-GSTSSVLQEVVVPIITNAQCRATS-YRSMIVDTMMCAGYVK 309
            |..:|| |.:....:|||.:::| |..|.||....||:|:|..|.... |..:|..:|:||||:|
  Rat   327 NSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLK 391

  Fly   310 TGGRDACQGDSGGPLIVRD-RIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
             ||.|:|||||||||:.:: |:::|.|..|||.|||:.:.||||||::.:|:||
  Rat   392 -GGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	90/232 (39%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	89/231 (39%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	14/74 (19%)
		Tryp_SPc	216..444	CDD:214473	90/232 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56985
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960