Protein Alignment CG4613 and HABP2

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 91/289 - (31%)
• Similarity: 140/289 - (48%)
• Gaps: 38/289 - (13%)

  Fly   100 SLSSSASPVFPLEGGGAKAFRV---NRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFL- 160
            |..|:....:|.|.....:.::   :.|.........:.||.||.:....|:||.|.:.....|
Human   274 SACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLT 338

  Fly   161 -------FCGGTLINDRYVLTAAHCVHGMDMRGVSVRLL----QLDRSSTHLGVTR-SVAFAHAH 213
                   ||||.||:..:|||||||.   |::...::::    .|.:...|....| ...|.::|
Human   339 ISMPQGHFCGGALIHPCWVLTAAHCT---DIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSH 400

  Fly   214 VGYDPVSLVHDIALLRLDQPIPLVD--------TMRPACLPSNWLQNFDFQKAIVAGWGLSQEGG 270
            .........:|||||:| :|   ||        .::..|||.....:  ..:..::|||:: |.|
Human   401 YNERDEIPHNDIALLKL-KP---VDGHCALESKYVKTVCLPDGSFPS--GSECHISGWGVT-ETG 458

  Fly   271 STSSVLQEVVVPIITNAQCRATS-YRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIV-RDRIFRL 333
            ..|..|.:..|.:|.|..|.:.. |..||.|:|:|||.::..|:|.|||||||||.. :|..:.:
Human   459 KGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYV 523

  Fly   334 AGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            .|:||:|..|.|  .|||||:|:::|.||
Human   524 YGIVSWGLECGK--RPGVYTQVTKFLNWI 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	84/248 (34%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056	1/2 (50%)
		Tryp_SPc	314..553	CDD:238113	85/249 (34%)