Protein Alignment CG4613 and PRSS55

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 89/306 - (29%)
• Similarity: 139/306 - (45%)
• Gaps: 51/306 - (16%)

  Fly    90 SDTASSLG---STSLSSSASPV-------------------FPLEGGGAKAFRVNRCASCTCGVP 132
            |:..|.:|   ||...:..|||                   ||.|.|....|.         |..
Human    32 SELLSRMGMRISTWKPAPPSPVPSSHWMLTKCFPFSFPLSFFPPECGDRSIFE---------GRT 87

  Fly   133 NVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDM--RGVSVRLLQLD 195
            ..:||.||.:....::||...|...:..||||:::|..::||||||::..::  ..:||.|...|
Human    88 RYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTND 152

  Fly   196 RSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACL-----PSNWLQNFDF 255
            .:|..:.: :.||....|..:...::.:|||||.|..||.|.|...|.||     |:.|
Human   153 LTSPSMEI-KEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATW------ 210

  Fly   256 QKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVKTGGRDACQGDS 320
            ::..|||||.:......|.....:..|::.......:.....:...|:|||| |....|||:|||
Human   211 RECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGY-KNESYDACKGDS 274

  Fly   321 GGPLIVR----DRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            ||||:..    ::.::: |::|:|..|.:.:.||:||.:..|..||
Human   275 GGPLVCTPEPGEKWYQV-GIISWGKSCGEKNTPGIYTSLVNYNLWI 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	73/236 (31%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	74/237 (31%)