Protein Alignment CG4613 and PRSS21

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 89/250 - (35%)
• Similarity: 129/250 - (51%)
• Gaps: 30/250 - (12%)

  Fly   135 NRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHG----MDMRGVSVRLLQLD 195
            :|||||......::||...:.......||.:|::.|:.||||||...    .|..|..|:..||.
Human    40 SRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLT 104

  Fly   196 RS----STHLGVTR----SVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQN 252
            ..    |.....||    ::..:..::|..|    :||||::|..|:.....::|.||.::   .
Human   105 SMPSFWSLQAYYTRYFVSNIYLSPRYLGNSP----YDIALVKLSAPVTYTKHIQPICLQAS---T 162

  Fly   253 FDFQKAI---VAGWGLSQEGGSTSS--VLQEVVVPIITNAQCR----ATSYRSMIVDTMMCAGYV 308
            |:|:...   |.|||..:|..:..|  .||||.|.||.|:.|.    ..|:|..|...|:|||..
Human   163 FEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNA 227

  Fly   309 KTGGRDACQGDSGGPLIV-RDRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            : ||:|||.|||||||.. ::.::...||||:|.||.:|:.|||||.:|.:.|||
Human   228 Q-GGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	87/247 (35%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	87/247 (35%)