Protein Alignment CG4613 and tmprss2

DIOPT Version :10

• Sequence 1: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: XP_004912265.1
• Gene: tmprss2 / 101731874
• XenbaseID: XB-GENE-22065907
• Length: 482
• Species: Xenopus tropicalis
• Alignment Length: 360
• Identity: 125/360 - (34%)
• Similarity: 171/360 - (47%)
• Gaps: 40/360 - (11%)

  Fly    19 DRSWAVYNYKP--PSRGYFYPKPERLPPLPVN-GSTTSSTGPPPGVQSDFIDDLIEGHKQQILSN 80
            |.|:.|..|.|  ..:.|.......||....| |.|....     |..|.      |:...:.|.
 Frog   139 DESYCVRTYGPGFQLQAYIAAASAWLPVCSDNWGDTLGRR-----VCQDM------GYSTYVRSG 192

  Fly    81 VLGVASETPSDTA-------SSLGSTSLSSSASPVFPLEGGGAKAFRVNRCASCTCGVPNV-NRI 137
            .:|.     ||:|       :|:....|.|.....|....|....    ||..|.....|| |||
 Frog   193 SVGA-----SDSAEGYLRLNTSVAEGKLQSRVYKSFVCTSGVVTL----RCIECGSSTKNVGNRI 248

  Fly   138 VGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDMRGV--SVRLLQLDRSSTH 200
            |||:|.....:||...:.......|||::|...|:|||||||.|:.....  :|.:..|.:|:
 Frog   249 VGGSQASLGDWPWQVSLQFNERHICGGSIITPNYILTAAHCVEGVYSSPYPWTVYVGSLYKST-- 311

  Fly   201 LGVTR-SVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWG 264
             |.|| ||.....|..||..:..:||||:||..||.|..|::|.|||:..:.....|....:|||
 Frog   312 -GGTRYSVKSLIGHQNYDTKTKNNDIALMRLKSPITLTSTVQPVCLPNAGMLWTSGQSCWTSGWG 375

  Fly   265 LSQEGGSTSSVLQEVVVPIITNAQC-RATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR- 327
            .:.|||::|.||...:||:|.:..| ||..|...:..||:||||:: ||.|:|||||||||:.:
 Frog   376 ATIEGGTSSGVLNAAMVPLIDSDTCNRAVVYNGAVTATMICAGYLR-GGIDSCQGDSGGPLVTKT 439

  Fly   328 DRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            ..::.|.|..|:|.|||..:.||||..::..|.||
 Frog   440 SSLWWLVGDTSWGTGCANMNKPGVYGNITELLPWI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	93/230 (40%)
tmprss2	XP_004912265.1	LDLa	112..143	CDD:238060	2/3 (67%)
		SRCR_2	148..241	CDD:464747	23/112 (21%)
		Tryp_SPc	248..474	CDD:238113	92/229 (40%)