DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4613 and tmprss2.14

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_031752402.1	Gene:	tmprss2.14 / 101731505	XenbaseID:	XB-GENE-22065937	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	101/294 - (34%)
Similarity:	154/294 - (52%)	Gaps:	24/294 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 TASSLGSTSLS-SSASPVFPLEGGGAKAFRVN----------------RCASCTCGVPNVNRIVG 139
            |::...|:.|| ||::..|.|:.........|                ||.||.......:||||
Frog   203 TSTYYESSHLSASSSNGYFMLQSSTVTGKLYNHLHYSATCASGNMVSLRCISCGLSTKVDSRIVG 267

  Fly   140 GTQVRTNKYPWIAQIIR--GTFLF-CGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRS-STH 200
            ||......:||..|:::  |..|: |||::|...:|:||||||:|......:.::.....: .::
Frog   268 GTVASAGDWPWQVQLLKRVGASLYLCGGSIITQHWVVTAAHCVYGSTSTPSAFKVFAGSLTIQSY 332

  Fly   201 LGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWGL 265
            .....:|..|..|..|...:..:|:|||:|...:.....:||.|||:..:...:.|...::|||.
Frog   333 YSAGYTVERALVHPSYSSYTQNYDVALLKLTAALVFTTNLRPVCLPNVGMPWAEGQPCWISGWGT 397

  Fly   266 SQEGGSTSSVLQEVVVPIITNAQC-RATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR-D 328
            :..|||.|:.|:...||:|::|.| :|..|...|..|||||||: :||.|.|||||||||:.: :
Frog   398 TSNGGSISTNLKAASVPLISSATCNQAAVYGGAISPTMMCAGYL-SGGTDTCQGDSGGPLVTKTN 461

  Fly   329 RIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            .::.|.|..|:||||...:.||||..::..||||
Frog   462 SLWWLVGDTSWGYGCGMTNKPGVYGNLTFSLEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	86/231 (37%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	85/230 (37%)
tmprss2.14	XP_031752402.1	LDLa	<96..121	CDD:238060
		LDLa	128..159	CDD:238060
		SRCR_2	164..259	CDD:406055	13/55 (24%)
		Tryp_SPc	265..497	CDD:238113	87/232 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010