DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4613 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	318	Identity:	107/318 - (33%)
Similarity:	155/318 - (48%)	Gaps:	49/318 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 VQSDFIDDLIE-GHKQQILSNVLGVASET-PSDTASSLGS-TSLSSSASPVFPLEGGGAKAFRVN 122
            ::.|:.::||. |..|......:.:.:.| .|.|..|||. |:|
Zfish   240 IEQDYQNNLISIGLNQTSFQQPVKIHNITNSSKTKCSLGMVTAL--------------------- 283

  Fly   123 RCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHG------ 181
            :|.:|........|||||......::||...:.......|||::|..|::|||||||:|
Zfish   284 KCIACGSRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWILTAAHCVYGIAYPMY 348

  Fly   182 -MDMRGVSVRLLQLDRSSTHLGVTRSVAFAHA----HVGYDPVSLVHDIALLRLDQPIPLVDTMR 241
             |...|:           |.|.:....|||..    |..|.|..|.|||||::|.||:.....:.
Zfish   349 WMVYAGL-----------TELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVE 402

  Fly   242 PACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQC-RATSYRSMIVDTMMCA 305
            |.|||:...|..|.:...::|||.:::||..|.......||:|:|..| :...|:..:...|:||
Zfish   403 PICLPNFGEQFEDGKMCWISGWGATEDGGDASVSQHCASVPLISNKACSQPEVYQGYLTAGMICA 467

  Fly   306 GYVKTGGRDACQGDSGGPLIVRD-RIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362
            ||: .||.|:|||||||||...| .|::|.|..|:|.|||:.:.||||||:::.|.||
Zfish   468 GYL-DGGTDSCQGDSGGPLACEDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	90/238 (38%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	89/237 (38%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	15/72 (21%)
		Tryp_SPc	298..525	CDD:238113	91/239 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56985
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910