Protein Alignment bbg and grip2a

DIOPT Version :9

• Sequence 1: NP_001246755.1
• Gene: bbg / 39583
• FlyBaseID: FBgn0087007
• Length: 2637
• Species: Drosophila melanogaster
• Sequence 2: XP_017212845.1
• Gene: grip2a / 568084
• ZFINID: ZDB-GENE-081104-132
• Length: 1100
• Species: Danio rerio
• Alignment Length: 1174
• Identity: 219/1174 - (18%)
• Similarity: 398/1174 - (33%)
• Gaps: 369/1174 - (31%)

  Fly  1595 KPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFP 1659
            |...|...|..:..|.::|.|...:.|..  .:..||.:|:.::..|
Zfish    55 KDDVPYTKGSKDTASDSSGFTNRCSLADE--QRGVTTVELIKKEGSS------------------ 99

  Fly  1660 PNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSL 1724
                         |.:|.       .||.|:...|.:....|.....|...     :||
Zfish   100 -------------LGLTI-------SGGCDKEGKPRVSNLRPGGLAARSDQ-----LNV------ 133

  Fly  1725 TRDYQRSLSGGTPRKPSDWRKDE--KSEKSVRDKIAMFSSNNELD-AIPPAPATAPISSSFTRKP 1786
             .||.:|::|   ...|..|.||  ...|::.:::.:     |:: .:||...:.|.|      .
Zfish   134 -GDYIKSVNG---INLSKLRHDEIISMLKNIGERVVL-----EVEYELPPFAPSNPCS------V 183

  Fly  1787 LNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHV-----ADSMYSLNTATP 1846
            ::::.|..|:...:|....|:         ......:..|:.|...:|     ||
Zfish   184 ISKTIEVCLEKEGNSFGFVLR---------GGFHEDWHKARPLVVTYVRPGGPAD---------- 229

  Fly  1847 TPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQL 1911
                       ..|:..:| :|.:|.:|...:......|:|.|::..:.:..            |
Zfish   230 -----------REGTLRAG-DRVLSVNGVAVNRQKHADALTLIMQSSQEAFF------------L 270

  Fly  1912 LEPILDLPEIKSQVKAASGEDSTD------SGLGESHRSTVNRNCQ------------------L 1952
            :|  .|: .:...|:.:||....|      |.||.|..:::.||.|                  |
Zfish   271 IE--YDI-MVMDSVQKSSGPLQVDIARSAGSVLGLSLSTSLYRNKQVITIQKIKPASVADRCGAL 332

  Fly  1953 GAG-------GAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQES 2010
            .||       |.:..:.|::...|......:|         |.|..|           |.|....
Zfish   333 HAGDILLAIDGMSTEHCSLMEAQQLLSSSSEL---------TKLEIL-----------PSLHSSQ 377

  Fly  2011 DTDSVFSHTARVATPPEKF-----ALTRTLSSETNTSIASSNTSTLTSGSSAGSQA----SCSSL 2066
            ||..|.....|.....|.:     |..:|.|:.:.|:...|:.| ::||.||.:..    :|.|.
Zfish   378 DTVRVQRSCQRQWDSSENYTNALPAFQKTPSAWSQTTPTPSHRS-VSSGVSANTSGFHSYNCGSQ 441

  Fly  2067 GSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDST----------DGE 2121
            .:.|                .....|:..|..:|.:|.:.|.|.:.:::.|:          .|:
Zfish   442 SAYP----------------NTYPSSTLPSYPSSPRCSATKRRHRRKEHKSSLSLASSTVGAGGQ 490

  Fly  2122 ACSLANR----RMKPISSYKLQQQQIQLGKQLVVDKLINVAA--YVELTSDTDDSSRRSDTPAKI 2180
            ...|.:.    |..|::.:.||.|    |.....:.|...||  ::|           .||||:.
Zfish   491 VVHLESAEVLLRGDPLTGFGLQLQ----GGVFATEPLSAPAAIRFIE-----------PDTPAER 540

  Fly  2181 SAMFIDEERKASFKGDPNQQA----------------KVKVEQVKPMVLPMLLPSA--------K 2221
            ..:....:|..|..|.|.:..                |:.:| |:..|...::||:        |
Zfish   541 CGVLQVGDRILSINGIPTEDGTLEEANQLLRDAALANKIALE-VEFDVAESVIPSSGTFQVKLPK 604

  Fly  2222 REPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNV 2286
            |..::...|....:|..:.... ::.|..| :.|::......:|..::|::
Zfish   605 RRGVELGITISASKKAGKPLII-SEIQKGS-IAHRIGTLEPGDRLLAIDNV-------------- 653

  Fly  2287 STTQETATEFGSFSSLGSNQSLITAQDVQQIV-------EEADPPLKTPEAFIIVLQRENPESSI 2344
                       ...:.|..::::..|..:.:|       |:....|::..:.|..::.:.....:
Zfish   654 -----------RLDNCGMEEAMMVLQQAEGMVKLRIQKDEDNLDELESSGSVIFTVELKRHGGPL 707

  Fly  2345 GITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEV 2409
            |||:: |::.....|.|..:..|..|.:.|.|..|||:||:|.||::|....|:|.:|:|....|
Zfish   708 GITIS-GTEEPFNPILISSLTRNGLAHRTGALHIGDRVLAINNMSLKGKPLSEAIHLLQTAGDTV 771

  Fly  2410 VL-VVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGES 2473
            .| :..||:.|:       .|..||.|......::::.:|..::.:...|     ||:..
Zfish   772 TLKIKKRSDPLL-------DSERGSPSRTASCVSDMEDDRSDSFRRGKYS-----DLLRQ----- 819

  Fly  2474 PVATTPSTGSVSPPQPASLHDEDAEATIAGIRAR-----------------RQLSRGDAAKLSTS 2521
               |||      |...:::...|:.|..||..::                 ||.:.       .|
Zfish   820 ---TTP------PSLDSAMDSWDSSALDAGYGSQGVYIHRPSDFTLHPSDWRQTNH-------RS 868

  Fly  2522 ELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSI-----EGGFDSPL----- 2576
            .|:.|....|..: .:.|...||...||.       |..:||..::.     |..:...|
Zfish   869 PLMSRRPAHRPTV-YDGRLSEEDWTYSGS-------VSPACGHNYNSTTDAQENYWSQALQDLET 925

  Fly  2577 -GNRPLI--VKKVFMGGAA-------QKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGP 2631
             |...::  ::...|.|:.       :|.|:.:.  :.|.::..:||..|..|.......:||..
Zfish   926 CGQSEILRELEATIMSGSTLSLGEDFEKQNESKT--KFLELSPENTSVNTPEDLKENSPSVPLEL 988

  Fly  2632 VKIC 2635
            .|||
Zfish   989 HKIC 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492	26/82 (32%)
		PDZ_signaling	2553..2634	CDD:238492	17/100 (17%)
grip2a	XP_017212845.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900