Protein Alignment bbg and PDZK1

DIOPT Version :9

• Sequence 1: NP_001246755.1
• Gene: bbg / 39583
• FlyBaseID: FBgn0087007
• Length: 2637
• Species: Drosophila melanogaster
• Sequence 2: XP_024303384.1
• Gene: PDZK1 / 5174
• HGNCID: 8821
• Length: 539
• Species: Homo sapiens
• Alignment Length: 652
• Identity: 131/652 - (20%)
• Similarity: 211/652 - (32%)
• Gaps: 248/652 - (38%)

  Fly   952 DEQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEG------------- 1003
            |:.::...|....:|.|.                  |.|.:.|..:||::||
Human     4 DKAELPSSPKVLVLTTEM------------------TSTFNPRECKLSKQEGQNYGFFLRIEKDT 50

  Fly  1004 ----LTTYTECETSEKESYLEGQQVLNGKGGFVSQDENSDQPTYEREVSETLT-IVNDGEKQVTK 1063
                :....:|..:||....:|.:||...|.||.::|:.......|:...::| :|.||
Human    51 EGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTLLVLDG------ 109

  Fly  1064 KLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVKKEAEKLYKLELADDDQGFDLSAFE 1128
                                              :||:|..|....|.:|..:..:||...:...
Human   110 ----------------------------------DSYEKAVKTRVDLKELGQSQKEQGLSDNILS 140

  Fly  1129 Q-----AEEEDKPEVSEEIKE-------VKDSQPVK----VDIQIEEEVKTPN------------ 1165
            .     .:...:|.:...:||       :|..|..|    .||       ||.
Human   141 PVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDI-------TPQGVAMRAGVLADD 198

  Fly  1166 ---QVIGEVKVEDV-NKEIKETVQVSQQE-----IKKEVKVSHQETKETFKSEEKDESNELKIVK 1221
               :|.|| .|||. ::|:.|.|:.|...     :.||....|.|.|..||.    |:..||::.
Human   199 HLIEVNGE-NVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKR----ETASLKLLP 258

  Fly  1222 EEVKVTHQD---------LR---EQ----IQEIEA---------------VKVVHKEVKVIKESA 1255
            .:.::....         ||   ||    |::|::               |.|..:.|:.:...:
Human   259 HQPRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDS 323

  Fly  1256 KVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPPLEDDLGYVLHKHIIFPQEKVKTA 1320
            .|.........|..:::.||..         :..::...||       ::.::....|...||.|
Human   324 VVEMIRKGGDQTSLLVVDKETD---------NMYRLAHFSP-------FLYYQSQELPNGSVKEA 372

  Fly  1321 PTPLPK--PKPKPPVPT----NKPKMPVNLTKPK-------SAPPPVPSKRSELSGSGGKPTPTQ 1372
            |.|.|.  ....||..|    :|||: ..|.|.:       :|...:|....:....||   |..
Human   373 PAPTPTSLEVSSPPDTTEEVDHKPKL-CRLAKGENGYGFHLNAIRGLPGSFIKEVQKGG---PAD 433

  Fly  1373 RRGSLETAQPPKPLERIIV---GVEQRDEP-EKPQPIINLASVDLPNVAPNSKQATV-------- 1425
            ..| ||.       |.:|:   ||...||| ||        .||  .:..:.|..|:
Human   434 LAG-LED-------EDVIIEVNGVNVLDEPYEK--------VVD--RIQSSGKNVTLLVCGKKAY 480

  Fly  1426 -----ETTPVV-------EMPPD-------ELQFESHQLPDDGEKEKDLHQESNDLLSGSSSSSV 1471
                 :..|:|       :.|||       |...:||.     .||:     ::...|.|||:|.
Human   481 DYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHM-----AKER-----AHSTASHSSSNSE 535

  Fly  1472 TT 1473
            .|
Human   536 DT 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375	4/24 (17%)
		PDZ_signaling	2331..2413	CDD:238492
		PDZ_signaling	2553..2634	CDD:238492
PDZK1	XP_024303384.1	PDZ_signaling	27..107	CDD:238492	17/79 (22%)
		PDZ	152..232	CDD:214570	20/87 (23%)
		PDZ_signaling	261..340	CDD:238492	11/78 (14%)
		PDZ	395..475	CDD:214570	26/101 (26%)
		F1-ATPase_gamma	<457..>501	CDD:320933	8/53 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900