Protein Alignment bbg and patj

DIOPT Version :10

• Sequence 1: NP_648705.2
• Gene: bbg / 39583
• FlyBaseID: FBgn0087007
• Length: 2637
• Species: Drosophila melanogaster
• Sequence 2: XP_005161760.2
• Gene: patj / 368723
• ZFINID: ZDB-GENE-030616-129
• Length: 1914
• Species: Danio rerio
• Alignment Length: 2170
• Identity: 419/2170 - (19%)
• Similarity: 705/2170 - (32%)
• Gaps: 698/2170 - (32%)

  Fly   761 LPTIGEVEEEFSSLEPQSLTNGNLVKSEE---SKKLPKMEVNAGGLAQLTDDKIADHDASATRA- 821
            :||:...|.: ..|:........||:.||   |.:|       |.|.:.....:..|..:...:
Zfish     5 VPTVSASERQ-QVLQALERLQSKLVQREEWTHSDRL-------GTLKEALQSPLFSHILTLQHSV 61

  Fly   822 -DTRDEVTTNQTQEISSSSSSSVKSQKTTTTTRVTTTKTSSSSSSSSCSSTVIPDVAFKLQPYEE 885
             ..:|:: .:...:..|..|.|.|.|..     |:.::.|||..|...:.|.:.:.:
Zfish    62 KQLKDQL-NSLPPDTCSEFSFSRKGQLI-----VSASRPSSSLGSVLSNGTALTNAS-------- 112

  Fly   886 RDDILSEPITTIHEERR--VLSEQKTLS-------ESRTRDALTGEEQLVTSANSKSSSARFKKI 941
             .:.|...|....:.|:  ::|.||.||       .....:.:.|....|......|.:.|..::
Zfish   113 -SEQLQRWIQAAAKGRKTELISLQKPLSGGLGFSVVGLRPEGVGGHGVFVRQVQPGSVADRDGRL 176

  Fly   942 SSNDNLLDLGD---EQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEG 1003
            ..||.:|.:..   :|.:.:|...|.:.|:   ::|:|.     .:.|.| .|..|   ||....
Zfish   177 LENDQILAINGIPLDQSVTQQQAIALLQQQ---KDRVEL-----VVARDT-ALKPR---LSASAP 229

  Fly  1004 LTTYTECETSEKESYLEGQ----QVLNGK-----------GGFVSQDENSDQPTYEREVSETLT- 1052
            :||.......|.|...:|.    .::.||           |....:|.......:...:.:|:|
Zfish   230 ITTDQWGHVEEIELVNDGSGLGFGIVGGKTTGMVVRTVVPGSVADKDGRLRTGDHILRIGDTMTR 294

  Fly  1053 -IVNDGEKQVTKKLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVK----------KE 1106
             :.:|   ||.:.|    :..|.....|:.:  |....:|.|.....:...|.          :.
Zfish   295 GLASD---QVVQVL----QACGAHVRMLIAR--EPLGAKQPAPPPAPAMGPVSSLPPPPPVPARR 350

  Fly  1107 AEKLYKLELADDDQGFDLSAFEQAEEEDKPEVSEEIKEVKDSQPVKVDIQIEEEVKTPNQVIGEV 1171
            |.:...||      ||::               .|:...|:.|.:.:.| |.....|....:|..
Zfish   351 ASRTPNLE------GFEI---------------HEVALKKEGQSLGISI-IGHNALTSEDAVGVY 393

  Fly  1172 KVEDVNKEIKE---TVQVSQQEIKKE-VKVSHQETKETFKSEEKDESNELKIVKEEVKVTHQDLR 1232
            ....:...|.|   .:|:..:.|..: |.:.....:|.           |:::|:...|.|..|.
Zfish   394 VKNVIPGSIAEQTGKIQIHDRIISLDGVNLQGYNNQEV-----------LEVMKQSGDVVHLTLV 447

  Fly  1233 EQIQEIEAVKVVHKEVKVIKESAKVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPP 1297
            .:|...:...:.....||.:||::|:...|.:..      ::.|.:.         :.||.|.|.
Zfish   448 RKIISPKRTTMEKSLDKVQRESSRVSLKRSSEMK------ARADQRG---------SVVESIDPA 497

  Fly  1298 LEDDLGYVLHKHIIFPQEKVKTAPTPLPKPKPKPPVPTNKPKMPVNLTKPKSAPPPVPSKRSELS 1362
            |..                                   .|.::..|:.:|.|.
Zfish   498 LSG-----------------------------------IKQQLQANMQEPASL------------ 515

  Fly  1363 GSGGKPTPTQRRGSLETAQPPK------PLERIIVGVEQRDEPEKPQPI------INLASVD--- 1412
                  |..:.|...|.|..|.      .|:.:|....:..:..|..||      :.|.|.|
Zfish   516 ------TEMELRAKWEQALGPHYDVMIVQLDPVIEDDIELQKYSKLLPIHTMRLGVELDSFDGHH 574

  Fly  1413 -LPNVAPNSKQATVETTPVVE----MPPDEL------------QFES----HQLPDD-------- 1448
             :..|||..        ||.:    .|.|||            :.||    .::|..
Zfish   575 YISTVAPEG--------PVAKHGLLRPEDELLEVNGVQLYGKSRRESVAFLREVPTPFTLVCCRR 631

  Fly  1449 -GEKEKDLHQESNDLLSGSSSSSVTTPITTPILVSATSSMDSVQ--------SVIEVV---NGMP 1501
             .:::.:.|.||.|..|.|....:...::  :|...||..||::        |.:|..   .|.|
Zfish   632 LAKEDNEYHPESEDWHSYSLQEQIEHNLS--MLARDTSLRDSIREEFQARQASAVEREVDDEGEP 694

  Fly  1502 I--IS------NQQTDDDDIDEVAAYDDG---------MHLEAEGTKDVRPVQEVTTLTLDREHE 1549
            :  ||      :|:.|||| :|....|:|         ..||.|     :..:.:....||.:..
Zfish   695 LEPISPEKEQMDQENDDDD-EEEEEEDEGELALWSPNVQVLELE-----KAERGLGFSILDYQDP 753

  Fly  1550 SDL------------GTLSNHHSNISSISGINASSNIPAATLISSSIKKTST----EAATTKPAA 1598
            .|:            |.::::|..|           .|...|:..:.....|    :|.....:|
Zfish   754 MDVARSVIVIRSLVPGGVADNHGGI-----------FPGDQLVFVNDTHLETCSLAQAVEVLKSA 807

  Fly  1599 PQIPGKM------ELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPP------TYSRL 1651
            |  |||:      .|.:.:.|:...:......:.:..|.||.     :|:..||      ..|.|
Zfish   808 P--PGKVYLGIRKPLAAEDRGSGQQSLWPVESVDEQPTAKQA-----VSHTLPPMPEDFVNGSIL 865

  Fly  1652 PPDGHEFP-------PNFSEPLIMHSHPLKVTTELSYEIQKG-GKDESSAPPLPKTGPPATVPRK 1708
            ..|..|.|       |.::.||        .|.:|..:::|. ..||.
Zfish   866 SDDLDEEPELILDAEPRYASPL--------TTVDLQPDVEKEMAVDEE----------------- 905

  Fly  1709 VYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKS-----------EKSVRDKIAMFSS 1762
              .:|:.:||......::....||......|...|.:...|           ::.|.|.::|
Zfish   906 --EEDVDVNVMEDQQSSKVNDTSLPSYLSEKIRSWEEPATSSRYHLNTEPDLQEQVDDDLSM--- 965

  Fly  1763 NNELDAIPPAPATAPI-----------SSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENL 1816
              .|:.|...|...|:           |.|.:|   |..||..|....:.||....:|
Zfish   966 --NLEKIQLQPLKIPLGHFTSWVETADSDSDSR---NEGSELTLTDTDNESAQRTSSR------- 1018

  Fly  1817 NDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSS------GVERRISFSGE 1875
            |..:|                    |.|.||  ...||.|..|....:      |..||:....|
Zfish  1019 NRKRR--------------------NQAGPT--RGDLPEREEGEGEETPVFSHWGPPRRVEVWAE 1061

  Fly  1876 GGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLP-------EIKSQVKAASGEDS 1933
            ..::..........:.:|.::..:|:|:.|.      :.:.|.|       :...::...||.|.
Zfish  1062 PEESLGISIVGGRTVIKRLKNGEELKGIFIK------QVLADSPAGRTGALKTGDKILQVSGVDL 1120

  Fly  1934 TDSGLGESHRSTVN--------------------RNCQLGAGGAANNYRSILNTNQRRPLEQQLS 1978
            .::    ||...|.                    |...:.|.       ||.....:|...|:..
Zfish  1121 QNA----SHEEAVQTIKAAPSPVVFIVQSLSSTPRPVSVTAS-------SIKQHKAKRKAAQKAG 1174

  Fly  1979 QPPAKPPRTSLTPLQPRSMMIPPPPPPLDQ------------ESDTDSVFSHTARVATPPEKFAL 2031
            |..|.||           |.:|||..|..|            |.||:.:   ..|.|..|.:..:
Zfish  1175 QGAAPPP-----------MRLPPPYRPPSQVQEEEQEQEEEDEQDTEVI---RQRYADLPGELLI 1225

  Fly  2032 TRTLSSETNTSIASSNTSTLTSGSSAGSQ-ASCSSL---GSTPAVDLTR--RV--------LKSQ 2082
            ...........:           |.||:: .||.|:   |.|.....:|  |:        :.:|
Zfish  1226 VELEKDRNGLGL-----------SLAGNRDRSCMSIFVVGITTGGPASRDGRIKVGDELLEINNQ 1279

  Fly  2083 VINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGK 2147
            |:.|       |....|||..:||.|:
Zfish  1280 VLYG-------RSHQNASAIIKSAASK-------------------------------------- 1299

  Fly  2148 QLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMV 2212
                .||:       |..:.|..::.:.||.        ..:.|.|......:....|...||.
Zfish  1300 ----VKLV-------LVRNEDAINQMAVTPF--------PSQPALFSSSETHENPPAVPAEKPQ- 1344

  Fly  2213 LPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQ------------------ 2259
            ||..||.::..|         .....:..|....|.:..|....:|.
Zfish  1345 LPESLPLSRSPP---------ENTLNKDQACVTATASSDPTHKSLTDGESAVKKLKPAEKLLESP 1400

  Fly  2260 -----KPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVE 2319
                 ||..|:..||..|..||:..|:.:..|:::..:....|            |:.|.:...:
Zfish  1401 SEQSAKPQVEQIPSLPKLQRSSTKPSTGSLEVTSSASSVPVSG------------TSPDFEYCSK 1453

  Fly  2320 E-ADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRIL 2383
            : |..|:...:..:|.:.:  ..|.:|:::.||.|.:...|.||::.....||:||||..||:||
Zfish  1454 DPATCPIVPGQETVIEISK--GRSGLGLSIVGGKDTQLDAIVIHEVYEEGAAARDGRLWAGDQIL 1516

  Fly  2384 AVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYER 2448
            .|||:.:|.:.|.::|:.|:...|:|.|.|.|.|:       :.|..    .:|:..|.||..:.
Zfish  1517 EVNGVDLRSVAHEDAIAALRQTPPKVRLTVLRDEA-------QYRDE----ENLDVFPVELQKKT 1570

  Fly  2449 KRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSP--------PQPASLHDED----AEATI 2501
            .|.         |.|.:|....|:....:....|..:.        .|..|:..||    ::.|:
Zfish  1571 GRG---------LGLSIVGKRNGKGVFISDVVKGGAADLDGRLMQGDQILSVDGEDMRQASQETV 1626

  Fly  2502 AGI------RARRQLSRGDAAKLSTSELLERAAEARNAIAA------------------------ 2536
            |.|      :...:|.|..||...:|....:.::..:|.|:
Zfish  1627 AAILKCARGKVLLELGRLKAASWISSRRTSQGSQMSHASASSSTPTPTPPTVAPPPSQTPNNNSR 1691

  Fly  2537 EIRAQAEDAAASGGGARCVEIVK-DSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRN 2600
            .|......:..:..|.|.|||.: .:..||.||.||..||||:.|:.:..:...|.|.||::::.
Zfish  1692 NIAEPISKSTVTEPGVRTVEITRGPTDALGISIAGGKGSPLGDIPIFIAMIQANGVAAKTHRLKV 1756

  Fly  2601 GDEILSINGASTSRMTRVDAWNYMK 2625
            ||.|:|||..|...:|..|..|.:|
Zfish  1757 GDRIVSINSQSLDGLTHADVVNMLK 1781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_648705.2	PDZ_canonical	90..177	CDD:467153
		PHA03247	<341..617	CDD:223021
		PTZ00341	<926..1237	CDD:173534	63/344 (18%)
		PDZ6_PDZD2-PDZ3_hPro-IL-16-like	2330..2415	CDD:467243	30/84 (36%)
		PDZ7_PDZD2-PDZ4_hPro-IL-16-like	2552..2636	CDD:467244	30/75 (40%)
patj	XP_005161760.2	None