DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bbg and Gopc

DIOPT Version :9

Sequence 1:	NP_001246755.1	Gene:	bbg / 39583	FlyBaseID:	FBgn0087007	Length:	2637	Species:	Drosophila melanogaster
Sequence 2:	NP_001101101.2	Gene:	Gopc / 309774	RGDID:	1309512	Length:	463	Species:	Rattus norvegicus

Alignment Length:	502	Identity:	108/502 - (21%)
Similarity:	201/502 - (40%)	Gaps:	107/502 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  2053 SGSSAGSQASCSSLGSTP-AVDLTR--RVLKSQ---------VINGEA------VALSSRKSILA 2099
            :||..|. ||| .:|.:| .|.:.|  .||:.:         ::.||.      :....|:.:.:
  Rat    11 AGSGPGG-ASC-PVGVSPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTS 73

  Fly  2100 SAKCRSA---KSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINV-AAY 2160
            .:.|.:.   |::...:.|...:.:...|.:...      :.|.:::.|.|: |.|:|:.: :..
  Rat    74 LSSCFAQLCHKAQTVSQINHKLEAQLVDLRSELT------ETQAEKVVLEKE-VHDQLLQLHSTQ 131

  Fly  2161 VELTSDTDDSSRRSDTPAKISAMFIDE-ERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREP 2224
            ::|.:.|..|.......||:|...::: ||:.    :.|:..|||..:::..|   .|...:.|.
  Rat   132 LQLHAKTGQSVDSGAIKAKLSVHSMEDLEREL----EANKTEKVKEARLEAEV---KLLRKENEA 189

  Fly  2225 LKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTT 2289
            |::.......|.:....||            |...|....|...:..|.....|.:.
  Rat   190 LRRHIAVLQAEVYGARLAA------------KYLDKELAGRVQQIQLLGRDMKGPAH-------- 234

  Fly  2290 QETATEFGSFSSLGSNQSLITA----QDVQQIVEEADPP------LKTPEAF----IIVLQRENP 2340
            .:...:..:...|..::::|.|    ||:::.::.  ||      ||..:..    .::|.:|:.
  Rat   235 DKLWNQLEAEIHLHRHKTVIRACRGRQDLKRPMQA--PPGHDQDSLKKSQGVGPIRKVLLLKEDH 297

  Fly  2341 ESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTP 2405
            | .:||::.||.:: ...|.|.:|....||.:.|.|..||.:|||||:::|...|:|::::|...
  Rat   298 E-GLGISITGGKEH-GVPILISEIHPGQPADRCGGLHVGDAVLAVNGVNLRDTKHKEAVTILSQQ 360

  Fly  2406 RP----EVVLVVTRSES----------------LVVKALTKKRSSLGSLSSLNEKPTELDYERKR 2450
            |.    |||.|....:|                |.:..|....:|..|....:.:...|....|:
  Rat   361 RGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNSGASCKDSSGEMKVLQGYNKK 425

  Fly  2451 NYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDA 2497
            ....|..:.|:      ..:||||:..|    :|....|.|||.:.|
  Rat   426 TVRDAHENGDV------GASGESPLDDT----AVRAAHPHSLHQKKA 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492	29/89 (33%)
		PDZ_signaling	2553..2634	CDD:238492
Gopc	NP_001101101.2	SMC_prok_B	<35..>215	CDD:274008	36/205 (18%)
Gopc	NP_001101101.2	PDZ_signaling	287..369	CDD:238492	27/83 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900