DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bbg and Tamalin

DIOPT Version :9

Sequence 1:	NP_001246755.1	Gene:	bbg / 39583	FlyBaseID:	FBgn0087007	Length:	2637	Species:	Drosophila melanogaster
Sequence 2:	NP_620249.1	Gene:	Tamalin / 192254	RGDID:	70554	Length:	394	Species:	Rattus norvegicus

Alignment Length:	388	Identity:	87/388 - (22%)
Similarity:	130/388 - (33%)	Gaps:	92/388 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1393 VEQRDEPEKPQPIINLASVDLPNVAPNSKQATVETT----PVVEMPP----DELQFESHQLPDDG 1449
            ::|::|.        .|:.||...||:|:.|....|    |....||    |||.
  Rat     9 LQQKEEA--------TAAPDLAGRAPDSEAARAAPTPSGPPAAAAPPGAPGDELY---------- 55

  Fly  1450 EKEKDLHQESNDLLSGSSSSSVTTPITTPI---LVSATSSMDSVQSVIEVVNGMPIISNQQTDDD 1511
            ...:|.|..  :|....:.|..|.|.....   ..:.|.|.:..:.|:.:..|     :.||..
  Rat    56 AALEDYHPA--ELYRALAVSGGTLPRRKGSGFRWKNFTQSPEQQRKVLTLEKG-----DNQTFG- 112

  Fly  1512 DIDEVAAYDDGMHLEAEGTKDVRPVQEVTTLT-LDREHESDLGTLS--NHHSNISSISGIN---- 1569
              .|:..|  |:|...|        |.|..:| :.|.|||....|:  .....|:|::|:|
  Rat   113 --FEIQTY--GLHHREE--------QRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGI 165

  Fly  1570 ----------ASSNI-PAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATH 1623
                      ||.|: ...||..:||:|...||        ::....:.|....|...:......
  Rat   166 RHREIVDIIKASGNVLRLETLYGTSIRKAELEA--------RLQYLKQTLYEKWGEYRSLMVQEQ 222

  Fly  1624 HLHQATTTKQLLVQDYLSYASPPTY-SRLPPDGHEFPPNFSEP--LIMHSHPLKVTTE--LSYEI 1683
            .|......|...:.|.|.......| :.|.|....|.|..:.|  ....|...|..|:  :.:..
  Rat   223 RLVHGLVVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAAPGGARGGSRRAKGDTDDAVYHTC 287

  Fly  1684 QKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSL---------SGGTP 1737
            ..||.:..:.||.|   |||..|.....:.....:.|||..|.....|:         .||.|
  Rat   288 FFGGAEPQALPPPP---PPARAPGPGSAETPASVLCPAPRATLSRSASVRCAGPGGGGGGGAP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492
		PDZ_signaling	2553..2634	CDD:238492
Tamalin	NP_620249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51		13/49 (27%)
		PDZ_signaling	99..184	CDD:238492	24/102 (24%)
		Interaction with PSCD3. /evidence=ECO:0000250	180..257		16/84 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..318		7/27 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900