DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bbg and mics-1

DIOPT Version :9

Sequence 1:	NP_001246755.1	Gene:	bbg / 39583	FlyBaseID:	FBgn0087007	Length:	2637	Species:	Drosophila melanogaster
Sequence 2:	NP_001343863.1	Gene:	mics-1 / 179475	WormBaseID:	WBGene00011890	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	68/320 - (21%)
Similarity:	104/320 - (32%)	Gaps:	131/320 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 GSGSSPTMEEQIENVTVFRLPGERLGFGLKFQGGTRSTELVQK--LYIQSCAADSPASKVSTSWG 138
            |..|.|     :|.:||..:.....|||....|||.:...|..  :|:.|..::      |.|:|
Worm    62 GQESVP-----LEALTVVEIEKTSKGFGFNIVGGTDNPHFVGDIGIYVSSVNSE------SKSYG 115

  Fly   139 NLREGDEIVSIDGRDVRELTRIDCVRGLKDNVAIKLVVRNGHGQKP-------PSEEDPQQQEHL 196
            .:|.||:|:|.||.|:...|..:.|...:.       |:.||..|.       ..:||..|....
Worm   116 VVRTGDKILSFDGIDMTYKTHDEAVEVFRS-------VKIGHVAKMLIDREYLHLQEDRTQTPTA 173

  Fly   197 SITLNAQPPPPPPVPPRKLVRRQNSKENQAQLLIEKPLTPPPDAEYYLNLLTESIKAGSESDDTA 261
            |:::..|..|           :..|.:|.                      |::.|:.|.|:
Worm   174 SVSITPQVTP-----------QTRSTQNN----------------------TDTPKSMSHSE--- 202

  Fly   262 STISTVIDKFSVGSNYSSDSSLNGHELAKVLQPFTLLEQEFLPLEQPLGHPKLLIPGNNYENVEF 326
                             |.|.|..|.|:.|:                             |.:..
Worm   203 -----------------SKSRLTSHGLSAVI-----------------------------ERIRG 221

  Fly   327 KTEKVNVYENVELRSPETTPTPKPRVQLATVEPKKRSII-PMPRKIPTPTKLPIEVTPPR 385
            |     |||..:.:|            :.:..|...||| .:||   ||.| |:.:..||
Worm   222 K-----VYEEEDAQS------------VTSYAPSTHSIIDDVPR---TPRK-PLSLLDPR 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492	24/88 (27%)
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492
		PDZ_signaling	2553..2634	CDD:238492
mics-1	NP_001343863.1	PDZ_signaling	71..145	CDD:238492	24/79 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900