DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bbg and Pdzd3

DIOPT Version :9

Sequence 1:	NP_001246755.1	Gene:	bbg / 39583	FlyBaseID:	FBgn0087007	Length:	2637	Species:	Drosophila melanogaster
Sequence 2:	NP_573489.2	Gene:	Pdzd3 / 170761	MGIID:	2429554	Length:	498	Species:	Mus musculus

Alignment Length:	334	Identity:	84/334 - (25%)
Similarity:	123/334 - (36%)	Gaps:	69/334 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  2305 NQSLITAQDVQQIVEEADP-PLKTPEAFIIVLQRENPESSIGITL---AGGSDYEAKEITIHKIL 2365
            |..|..|:|..|    :|| .|..|. |.::.:.|  |.:.|..|   .|.:|:     .:.::.
Mouse    27 NPVLSLAEDQDQ----SDPWNLHRPR-FCLLSKEE--EKTFGFHLQQHLGKADH-----VVCRVD 79

  Fly  2366 SNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSS 2430
            ..|.|.:.| |::||||||||...:....|...:..::...|.|:|.|     |........|..
Mouse    80 PGTSAQRQG-LREGDRILAVNNNIVAHEDHAVVVRYIRASGPRVLLTV-----LAQHVHDVARVL 138

  Fly  2431 LGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAG---------ESPVATTPSTGSVS- 2485
            .||.:.|  .||.....|.|..|           :|.:|.|         ..|.....|.|..:
Mouse   139 QGSDAFL--CPTLPSGVRPRLCH-----------VVKDEGGFGFSVTHGSRGPFWLVLSAGGAAE 190

  Fly  2486 ----PPQPASLHDEDAEATIAGIR--ARRQLSR-----GDAAKLSTSELLERAAEARNAIAAEIR 2539
                ||....|     |...|.:.  ...||:|     ||...|..:.|  ...|..:.:...:.
Mouse   191 RAGVPPGARLL-----EVNGASVEKLTYNQLNRKLWQSGDQVTLLVAGL--EVEEQCHQLGMPLA 248

  Fly  2540 AQAEDAAASGGGARCVEIVKDSCGLGFSI--EGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGD 2602
            |...:..|.....||:.|.|...|.||.:  |.|.|..||.   .:..|..|..|.|.. ::.||
Mouse   249 APLAEGWALPAKPRCLNIEKGPEGFGFLLREEKGLDGRLGQ---FLWDVDPGLPADKAG-MKAGD 309

  Fly  2603 EILSINGAS 2611
            .::::.|.|
Mouse   310 RLVAVAGES 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492	23/84 (27%)
		PDZ_signaling	2553..2634	CDD:238492	20/61 (33%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492	25/93 (27%)
		PDZ_signaling	155..232	CDD:238492	19/92 (21%)
		PDZ	260..345	CDD:214570	20/63 (32%)
		PDZ_signaling	407..471	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900