DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bbg and Slc9a3r2

DIOPT Version :9

Sequence 1:	NP_001246755.1	Gene:	bbg / 39583	FlyBaseID:	FBgn0087007	Length:	2637	Species:	Drosophila melanogaster
Sequence 2:	NP_446263.2	Gene:	Slc9a3r2 / 116501	RGDID:	620380	Length:	337	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	63/292 - (21%)
Similarity:	103/292 - (35%)	Gaps:	99/292 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  2361 IHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVV------------ 2413
            |.::...:| |:...|:.|||::.|||:::.|.||.:.:..:|....:..|:|
  Rat    36 IRRVEPGSP-AEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRR 99

  Fly  2414 --TRSESLVVKALTKKRS------------SLGS---LSSLNEKPTELDYERKRNYH--KASRSL 2459
              |.:|.:..:.|....:            ||||   ...:|..|.||   |.|..|  :..:..
  Rat   100 QLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGQKDVNGPPREL---RPRLCHLRRGPQGY 161

  Fly  2460 DLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELL 2524
            ..:|....:..|:       ...||.|..||||         :|:||:.:|...:...:   |.|
  Rat   162 GFNLHSDKSRPGQ-------YIRSVDPGSPASL---------SGLRAQDRLIEVNGQNV---EGL 207

  Fly  2525 ERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFS----------IEGGFDSPLGNR 2579
            ..|     .:.|.|:||.::|.        :.:|.......|.          :||...||
  Rat   208 RHA-----EVVARIKAQEDEAR--------LLVVDPETDEHFKRLRVVPTEDHVEGPLPSP---- 255

  Fly  2580 PLIVKKVFMGGAAQKTNQVRNGDEILSINGAS 2611
                              |.||..:..:||.|
  Rat   256 ------------------VTNGTSLAQLNGGS 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492	15/51 (29%)
		PDZ_signaling	2553..2634	CDD:238492	12/69 (17%)
Slc9a3r2	NP_446263.2	PDZ_signaling	9..88	CDD:238492	15/52 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..146		6/18 (33%)
		PDZ_signaling	149..228	CDD:238492	23/110 (21%)
		EBP50_C	232..337	CDD:401087	11/60 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..337		10/46 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900