DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bbg and cytip

DIOPT Version :9

Sequence 1:	NP_001246755.1	Gene:	bbg / 39583	FlyBaseID:	FBgn0087007	Length:	2637	Species:	Drosophila melanogaster
Sequence 2:	XP_003199223.2	Gene:	cytip / 100537036	ZFINID:	ZDB-GENE-140106-76	Length:	343	Species:	Danio rerio

Alignment Length:	236	Identity:	62/236 - (26%)
Similarity:	106/236 - (44%)	Gaps:	45/236 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  2264 ERFSSLDSLASSSS----GVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPP 2324
            ::.|||||....||    .:....::.|:.:...||.....:|  :||.:.......:|:..|
Zfish    13 KQMSSLDSYIIDSSQKKRSILWRQRSFSSPKNLNTEGMKGRTL--SQSQLARTHSNSLVDYTD-- 73

  Fly  2325 LKTPEAFIIVLQRENPE------SSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRIL 2383
               |:..::||::::.|      .:.|:.:...|..|.  .|....:.:..||:...|..||.||
Zfish    74 ---PQRTMVVLEKQDNEVFGFEVQTYGLKVKNTSMVEM--CTFVCRVQDGSAAETAGLTAGDIIL 133

  Fly  2384 AVNGMSMRGLTH-------RESISVLKTPRPEVVLVVTRSESLVVK-ALTKKRSSLGSLSSLNEK 2440
            :|||:|:.|.||       |||.:.||        :.|.|.|::.: .|.||...|  ..:|.||
Zfish   134 SVNGVSIEGSTHQNIIELIRESSNTLK--------LETVSGSVMKRIELEKKMHYL--KQTLREK 188

  Fly  2441 PTELD---YERKR----NYHKASRSLDLDLDL-VSNEAGES 2473
            ..||.   .:.||    |.:::::.|.:|..: :|:..|.|
Zfish   189 WVELQSLTLKEKRLTQGNLNESAQYLSVDSVMSLSSPMGRS 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbg	NP_001246755.1	PDZ_signaling	90..177	CDD:238492
		ATP-synt_B	<1084..>1109	CDD:304375
		PDZ_signaling	2331..2413	CDD:238492	26/94 (28%)
		PDZ_signaling	2553..2634	CDD:238492
cytip	XP_003199223.2	PDZ_signaling	78..162	CDD:238492	26/93 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900