DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stwl and madf-4

DIOPT Version :9

Sequence 1:	NP_001261839.1	Gene:	stwl / 39581	FlyBaseID:	FBgn0003459	Length:	1037	Species:	Drosophila melanogaster
Sequence 2:	NP_505565.3	Gene:	madf-4 / 179386	WormBaseID:	WBGene00011575	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	48/226 - (21%)
Similarity:	90/226 - (39%)	Gaps:	29/226 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EVNLMLLRSVEKQTALYDRTDENYRKRLPSENAWDMVASEV---GESVEKCKRRWRQLRNDYTRW 67
            :..|.|:.||::...:|:|.|..::........|.:::.|:   |:.|| .:|:|:.:|:.|.|.
Worm    17 DFTLALIDSVQRNPCVYNRYDPLHKVTDYKHEIWKLISIEIGYDGQPVE-LERKWKHMRDKYVRL 80

  Fly    68 CNADANRRRNGQRRLAYPLADELRFLDRHLNIADDMAADDDRSVSSDKDRDNNRDSEGVDHHAQ- 131
            ...|..:....:....|....::.|||.::         :.|:....||..|:...:.:|....
Worm    81 RKQDKQKAPIKKTNKWYNYYHKMSFLDPYV---------EHRNRKRQKDYLNSNTPDFLDDDTAF 136

  Fly   132 ---ASLKERASSTSKLVKEVKLASQVRKEKSSQDKRENWENPGDKQRSRKKSAEEKLNDLEESDE 193
               .|:||.....|.|.......:......||.....|  |.|       :..:....|:|: |:
Worm   137 LDGLSVKEMLKPESLLTSNDAGYNSPHTTSSSSSSGSN--NNG-------RFLDSPTIDIED-DK 191

  Fly   194 PEKVPELDSFL--QSDNEDDECMDEEHLEDL 222
            .......|.|:  |::||.:.....:|.:||
Worm   192 KNLALIYDKFVANQTENEKNHRFSNKHGKDL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stwl	NP_001261839.1	MADF	11..98	CDD:214738	21/89 (24%)
stwl	NP_001261839.1	BESS	604..637	CDD:281011
madf-4	NP_505565.3	MADF	22..111	CDD:214738	21/98 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910