DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7768 and PPIB

DIOPT Version :9

Sequence 1:	NP_648697.1	Gene:	CG7768 / 39573	FlyBaseID:	FBgn0036415	Length:	164	Species:	Drosophila melanogaster
Sequence 2:	NP_000933.1	Gene:	PPIB / 5479	HGNCID:	9255	Length:	216	Species:	Homo sapiens

Alignment Length:	162	Identity:	104/162 - (64%)
Similarity:	124/162 - (76%)	Gaps:	3/162 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVYFDIAAGGEKLGRIVMELRSDVVPKTAENFRALCTGEKGYGYKGSPFHRVIPNFMCQGGDFTN 69
            :||||:..|.|.:||::..|....||||.:||.||.|||||:|||.|.|||||.:||.||||||.
Human    45 KVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTR 109

  Fly    70 QNGTGGRSIYGNKFPDENFELKHTGAGVLSMANAGANTNGSQFFICTGKTTWLDNKHVVFGKVVE 134
            .:||||:||||.:||||||:|||.|.|.:||||||.:||||||||.|.||.|||.||||||||:|
Human   110 GDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLE 174

  Fly   135 GMDIVQKVES--YGSQDGKTSKKVIIEDCGAL 164
            ||::|:||||  ..|:| |..|.|||.|||.:
Human   175 GMEVVRKVESTKTDSRD-KPLKDVIIADCGKI 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7768	NP_648697.1	cyclophilin_ABH_like	4..162	CDD:238907	102/158 (65%)
PPIB	NP_000933.1	cyclophilin_ABH_like	45..203	CDD:238907	102/158 (65%)
PPIB	NP_000933.1	Prevents secretion from ER	213..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830