DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7768 and PPIE

DIOPT Version :9

Sequence 1:	NP_648697.1	Gene:	CG7768 / 39573	FlyBaseID:	FBgn0036415	Length:	164	Species:	Drosophila melanogaster
Sequence 2:	NP_001181936.1	Gene:	PPIE / 10450	HGNCID:	9258	Length:	314	Species:	Homo sapiens

Alignment Length:	153	Identity:	104/153 - (67%)
Similarity:	121/153 - (79%)	Gaps:	2/153 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLPRVYFDIAAGGEKLGRIVMELRSDVVPKTAENFRALCTGEKGYGYKGSPFHRVIPNFMCQGGD 66
            |.|:||.||..|.:..|||.|.|||||||.||||||.|||.|||:|:|||.|||:||.|||||||
Human   138 SNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGD 202

  Fly    67 FTNQNGTGGRSIYGNKFPDENFELKHTGAGVLSMANAGANTNGSQFFICTGKTTWLDNKHVVFGK 131
            |||.|||||:||||.||.||||.|||||.|:|||||:|.||||||||:...||.|||.||||||:
Human   203 FTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGE 267

  Fly   132 VVEGMDIVQKVESYGSQDGKTSK 154
            |.||:|:::::|.  :.|.|.||
Human   268 VTEGLDVLRQIEV--APDTKASK 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7768	NP_648697.1	cyclophilin_ABH_like	4..162	CDD:238907	103/151 (68%)
PPIE	NP_001181936.1	RRM	<5..>84	CDD:223796
		RRM_PPIE	8..80	CDD:240793
		cyclophilin_ABH_like	140..279	CDD:238907	98/138 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53630
OrthoDB	1	1.010	-	-		D563773at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830