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Protein Alignment nan and TRPV1

DIOPT Version :9

Sequence 1:	NP_001261833.1	Gene:	nan / 39571	FlyBaseID:	FBgn0036414	Length:	834	Species:	Drosophila melanogaster
Sequence 2:	NP_061197.4	Gene:	TRPV1 / 7442	HGNCID:	12716	Length:	839	Species:	Homo sapiens

Alignment Length:	798	Identity:	190/798 - (23%)
Similarity:	303/798 - (37%)	Gaps:	248/798 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 DYCPEVSEAEYIS------NPTAYRFVCWD-----------LNMRGAVGETILH---------LC 146
            |.||.::.:..|:      .||..|.:..|           |..|.::.|.:..         |.
Human    71 DSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQNNCQDLESLLL 135

  Fly   147 LLNASSLHAD-------------LAKRLLKFYP------KLILDI--------------YMSDEY 178
            .|..|..|..             |.|.:|..:.      .|:|:|              |....|
Human   136 FLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYY 200

  Fly   179 YGESVLHIAIVNEDPAMVKYLLDANADVQERCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDG 243
            .|::.|||||...:.|:|..|::..||||....|.|       |.:|             ....|
Human   201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDF-------FKKT-------------KGRPG 245

  Fly   244 YVYWGEYPLSFAACLSQEECFRLVLARG---ADPDFQDTNGNTVLHMLV---------------I 290
            : |:||.|||.|||.:|....:.:|...   ||...:|:.||||||.||               :
Human   246 F-YFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSM 309

  Fly   291 YEKIEMFDVGYEVGTNIH-------IKNIQNLTPLTLAAKLGRVEMFFHVMSIEREIY------- 341
            |.:|.|      :|..:|       :.|.:.:|||.|||..|::.:..::  ::|||.
Human   310 YNEILM------LGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYI--LQREIQEPECRHL 366

  Fly   342 ------WQLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVFGDK---LEHLELLDGVVIDLLK 397
                  |..|.:..:.|.|..|||       ..|:|||..:.:...   ..|..||...:..||:
Human   367 SRKFTEWAYGPVHSSLYDLSCIDT-------CEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQ 424

  Fly   398 TKWDTFCKSRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGANSTTAKSDLYRQNGSDSYHL 462
            .|||.|.|..||..|.::.||.:|
Human   425 DKWDRFVKRIFYFNFLVYCLYMII----------------------------------------- 448

  Fly   463 HSKRATMTTEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNLESDLAKLRIMAELLNFVGAI 527
                           .....||.|  |:.||.:          .:|......|:..|:|:.:|.:
Human   449 ---------------FTMAAYYRP--VDGLPPF----------KMEKTGDYFRVTGEILSVLGGV 486

  Fly   528 LYLLVALREARFLGLKMFIEN-------LMTAPSRVMFLFSCALMMTIPWLRVSCLTEIDDHVTV 585
            .:.        |.|::.|::.       .:.:.|.::|......|:....|..|.|.|   :|..
Human   487 YFF--------FRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKE---YVAS 540

  Fly   586 VIMLTTAPY--FLFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMGFSQAFYIIFLTFDNP 648
            ::......:  .|::.|||:.:|.:.|||.:|::.||.||:.:|:||:.|||.|...:.....|.
Human   541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKND 605

  Fly   649 SSPEDQDAE------SNPMPSPMESIVAMFLMSLTNFGDYYGAMVSTQHEYEAKILFFL----FM 703
            |.|.:..:.      ..|..|...|:.:..| .|..|....|.:..|:: |:.|.:|.:    ::
Human   606 SLPSESTSHRWRGPACRPPDSSYNSLYSTCL-ELFKFTIGMGDLEFTEN-YDFKAVFIILLLAYV 668

  Fly   704 VIVSVLLVNMLIAMMGNTYQKIA-EIRNEWQRQWARIVLVVERSVPPAERLKNFMQYSQSMSDGR 767
            ::..:||:|||||:||.|..||| |.:|.|:.|.|..:|..|:|.....| |.|          |
Human   669 ILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMR-KAF----------R 722

  Fly   768 RALVLRLNMTEEEKEEMK 785
            ...:|::..|.:.|::.:
Human   723 SGKLLQVGYTPDGKDDYR 740

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.