Protein Alignment nan and ocr-4

DIOPT Version :10

• Sequence 1: NP_001261833.1
• Gene: nan / 39571
• FlyBaseID: FBgn0036414
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: NP_501172.2
• Gene: ocr-4 / 177506
• WormBaseID: WBGene00003841
• Length: 756
• Species: Caenorhabditis elegans
• Alignment Length: 843
• Identity: 324/843 - (38%)
• Similarity: 464/843 - (55%)
• Gaps: 113/843 - (13%)

  Fly     1 MGNTESNVTSGVKKQAGVSTQALYKFVNLKGGGLLVDMMKRACQTKQFAEIDHAIKTKVEPFLYN 65
            |||..|.||:|:|.|...|..|:.|..::.|.|.|.|:...|.:|....|:|..|..||:|.|||
 Worm     1 MGNASSAVTAGIKNQVNASNNAINKLADMSGRGFLADLAMDAVRTGNHEELDKQILEKVQPMLYN 65

  Fly    66 KGAGRYFPISKLVLLRNRDRP-RTRQLPEIRALENPDDDFNIHDYCPEVSEAEYISNPTAYRFVC 129
            .|.|...|:|.|:..|:::|. .|..:|                 .|.          |..||:|
 Worm    66 NGQGEMIPLSDLIAQRHKERTGNTFAVP-----------------VPS----------TECRFIC 103

  Fly   130 WDLNMRGAVGETILHLCLLNASSLHAD-LAKRLLKFYPKLILDIYMSDEYYGESVLHIAIVNEDP 193
            |.||.|||||||:||.|.|.....|.. ||:||:..:||:|.|.|:|||||||:|||:.||:|:.
 Worm   104 WKLNSRGAVGETLLHTCFLAGLPNHMKLLAERLIAIFPKIINDFYLSDEYYGETVLHMGIVSENA 168

  Fly   194 AMVKYLLDANADVQERCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDGYVYWGEYPLSFAACL 258
            ..|:|||.:.|||..||.|.|.:.:|.|.||||.|:.|:..:...|.|.|::|||||||||||||
 Worm   169 EFVRYLLKSGADVHARCSGNFFTCDDQKGSRTDHPEVEHAIISKHTKYPGHIYWGEYPLSFAACL 233

  Fly   259 SQEECFRLVLARGADPDFQDTNGNTVLHMLVIYEKIEMFDVGYEVGTNIHIKNIQNLTPLTLAAK 323
            ||.||.|:::|.|||.:..||||||:||:..|:|..|||.:...:|.::||:|.||||||||||.
 Worm   234 SQPECIRMLVAHGADVNAADTNGNTILHICTIHENYEMFKMALSLGADLHIQNRQNLTPLTLAAF 298

  Fly   324 LGRVEMFFHVMSIEREIYWQLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVFGDKLEHLELL 388
            |.:.||...::..||.:.|..|....|||||..:|:|...:|:||:.|||...|:|:|:|||.||
 Worm   299 LAKKEMMQRIVEEERTVNWTYGRTQSAAYPLEHVDSIEPTSGSINQKSVLTIAVYGEKVEHLSLL 363

  Fly   389 DGVVIDLLKTKWDTFCKSRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGANSTTAKSDLYR 453
            ..::..|:..||..:.:...:.|..||.:||:.....|:|||.|  .:..:..||......|...
 Worm   364 PHLLEQLVHHKWIAYGRKTLFAQLSMFCIYFICVTSCFLLRPSP--FERQQHIANDLICFYDFKT 426

  Fly   454 QNGSDS------YHLHSKRATMTTEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNLESDLA 512
            :..::|      |||
 Worm   427 RRFNESAVSTIIYHL-------------------------------------------------- 441

  Fly   513 KLRIMAELLNFVGAILYLLVALREARFLGLKMFIENLMTAPSRVMFLFSCALMMTIPWLRVSCLT 577
                 ..|:...||.|||:.||...:.:|..:::..|...|::.:|||||.||:...:||:.||.
 Worm   442 -----LHLICVTGATLYLVQALLHIKNVGYHLYVLGLSGFPAKAIFLFSCILMVITFFLRIFCLD 501

  Fly   578 EIDDHVTVVIMLTTAPYFLFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMGFSQAFYIIF 642
            |.:|.|.:||:|.|:..|||||||||:|||||:|:|::::.||:||..||||.|:|||||||:||
 Worm   502 EAEDIVWIVIVLLTSLKFLFFCRGFKSVGPFVLMLYKIIIRDLMRFFLIYLVIVVGFSQAFYVIF 566

  Fly   643 LTFDNPSSPEDQDAESNPMPSPMESIVAMFLMSLTNFGDYYGAMVSTQHEYEAKILFFLFMVIVS 707
            |.:....|   .:.|.:.|.:..||.|.||:||||.|..::..:...:|....||.|.::|::|:
 Worm   567 LGYKRSDS---GNREPSIMSNVAESYVRMFIMSLTEFTVFFEQLEECEHTVIGKITFVVYMLLVT 628

  Fly   708 VLLVNMLIAMMGNTYQKIAEIRNEWQRQWARIVLVVERSVPPAERLKNFMQYSQSMSDGRR-ALV 771
            :||:|||||||.|||.:::....||.|||:.|:|::|:|..||.||:...:|......|.: .|:
 Worm   629 LLLINMLIAMMTNTYTEVSGNSLEWLRQWSAIILMMEQSFDPATRLRYQRRYGIRFDGGEKLVLL 693

  Fly   772 LRLNMTEEEKEEMKEVQEMKRIHQRFAKKRQMEREARALRRQQEYEKFFGTAPKSECSDNNNF 834
            |:..|||||.|     .:.|::|:   ::|:...|.|..:|::         |...|....|:
 Worm   694 LKDKMTEEEFE-----CQRKKMHE---ERRKFREELRTNQRRR---------PVFICKQGANY 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nan	NP_001261833.1	TRPV	131..748	CDD:454755	259/623 (42%)
		ANK repeat	138..174	CDD:293786	17/36 (47%)
		ANK repeat	179..229	CDD:293786	26/49 (53%)
		ANK repeat	231..278	CDD:293786	26/46 (57%)
		ANK repeat	280..311	CDD:293786	14/30 (47%)
ocr-4	NP_501172.2	TRPV	109..665	CDD:454755	255/615 (41%)
		ANK repeat	154..194	CDD:293786	20/39 (51%)
		ANK repeat	196..253	CDD:293786	32/56 (57%)
		ANK repeat	255..286	CDD:293786	14/30 (47%)