| Sequence 1: | NP_001261833.1 | Gene: | nan / 39571 | FlyBaseID: | FBgn0036414 | Length: | 834 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_446239.3 | Gene: | Trpv5 / 116469 | RGDID: | 620636 | Length: | 723 | Species: | Rattus norvegicus |
| Alignment Length: | 714 | Identity: | 196/714 - (27%) |
|---|---|---|---|
| Similarity: | 319/714 - (44%) | Gaps: | 139/714 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 131 DLNMRGAVGETILHLCLLNASSLHADLAKRLLKFYPKLILDIYMSDEYYGESVLHIAIVNEDPAM 195
Fly 196 VKYLLDANADVQERCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDGYVYWGEYPLSFAACLSQ 260
Fly 261 EECFRLVLARGADPDFQDTNGNTVLHMLVI----------YEKIEMFDVGYEVGTNIHIKNIQNL 315
Fly 316 TPLTLAAKLGRVEMFFHVMSIEREIYWQLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVFGD 380
Fly 381 KLEHLELLDGV-VIDLLKTKWDTFCKSRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGANS 444
Fly 445 TTAKSDLYRQNGSDSYHLHSKRATMTTEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNLES 509
Fly 510 DLAKLRIMAELLNFVGAILYLLVALREARFLGL-KMFIENLMTAPSRVMFLFSCALMMTIPWLRV 573
Fly 574 SCLTEIDDHVTVVIMLTTAPY--FLFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMGFSQ 636
Fly 637 AFYIIFLTFDNPSSPEDQDAESNPMPSPMESIVAMFLMSLTNFGDYYGAMVSTQHEYEAKILFFL 701
Fly 702 FMVIVSVLLVNMLIAMMGNTYQKIAEIRNE-WQRQWARIVLVVERSVPP---------------A 750
Fly 751 ERLKNFMQYSQSMSDGRRALVLRL--NMTEEEKEEMKEVQEMKRIHQRFAKKRQMEREARALRR 812 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| nan | NP_001261833.1 | Ank_2 | <131..209 | CDD:289560 | 26/77 (34%) |
| ANK | <131..200 | CDD:238125 | 23/68 (34%) | ||
| ANK repeat | 138..174 | CDD:293786 | 11/35 (31%) | ||
| ANK | 178..329 | CDD:238125 | 53/160 (33%) | ||
| ANK repeat | 179..229 | CDD:293786 | 15/49 (31%) | ||
| Ank_2 | 184..311 | CDD:289560 | 44/136 (32%) | ||
| ANK repeat | 231..278 | CDD:293786 | 17/46 (37%) | ||
| ANK repeat | 280..311 | CDD:293786 | 11/40 (28%) | ||
| Ion_trans | 519..727 | CDD:278921 | 64/210 (30%) | ||
| Trpv5 | NP_446239.3 | TRPV5-6 | 23..630 | CDD:411976 | 183/659 (28%) |
| ANK 1. /evidence=ECO:0000255 | 72..101 | 11/31 (35%) | |||
| ANK repeat | 73..107 | CDD:293786 | 11/36 (31%) | ||
| ANK 2. /evidence=ECO:0000255 | 110..139 | 11/28 (39%) | |||
| ANK repeat | 111..154 | CDD:293786 | 15/64 (23%) | ||
| ANK repeat | 156..187 | CDD:293786 | 16/30 (53%) | ||
| ANK 3. /evidence=ECO:0000255 | 156..185 | 16/28 (57%) | |||
| ANK 4. /evidence=ECO:0000255 | 189..222 | 11/32 (34%) | |||
| ANK repeat | 189..219 | CDD:293786 | 10/29 (34%) | ||
| ANK 5. /evidence=ECO:0000255 | 232..261 | 12/28 (43%) | |||
| Interaction with S100A10. /evidence=ECO:0000250|UniProtKB:P69744 | 591..595 | 0/3 (0%) | |||
| CBD_TRPV5_C | 642..719 | CDD:412091 | 8/39 (21%) | ||
| Involved in Ca(2+)-dependent inactivation. /evidence=ECO:0000250 | 643..646 | 0/2 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 651..674 | 6/30 (20%) | |||
| Involved in Ca(2+)-dependent inactivation. /evidence=ECO:0000250 | 693..723 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166338792 | |
| Domainoid | 1 | 1.000 | 110 | 1.000 | Domainoid score | I6174 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3676 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 228 | 1.000 | Inparanoid score | I3382 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D386733at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001377 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm8914 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105955 | |
| Panther | 1 | 1.100 | - | - | O | PTHR10582 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X396 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.760 | |||||