Protein Alignment nan and LOC105947301

DIOPT Version :10

• Sequence 1: NP_001261833.1
• Gene: nan / 39571
• FlyBaseID: FBgn0036414
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: XP_017949519.2
• Gene: LOC105947301 / 105947301
• XenbaseID: XB-GENE-29089515
• Length: 639
• Species: Xenopus tropicalis
• Alignment Length: 651
• Identity: 163/651 - (25%)
• Similarity: 278/651 - (42%)
• Gaps: 147/651 - (22%)

  Fly   130 WDLNMRGAVGETILHLCLLNASSLHADLAKRLLKFYPKLILDIYMSDEYYGESVLHIAIVNEDPA 194
            :|..::||:||.:||:..|..::   ::...||..:|.||......|.|.||:.|||||||::..
 Frog    45 FDPTIKGALGENVLHIAALYNNN---EILVELLDAFPFLINKPIECDAYKGETALHIAIVNQNAE 106

  Fly   195 MVKYLLDANADVQE-RCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDGYVYWGEYPLSFAACL 258
            ||:.|:...||::. |..|.|.           :|..:           |..|:|||..||||.:
 Frog   107 MVRELIARKADMENARATGNFF-----------APRRK-----------GQHYYGEYVTSFAAYV 149

  Fly   259 SQEECFRLVLARGADPDFQDTNGNTVLHMLVIYEKIEMFDVGYEVGTNI-------HIKNIQN-- 314
            ..:|..:.::...|..:.||:.||||.|:||:::...|....|:....|       :::.|.|
 Frog   150 GNQEILQTLVENEAPLETQDSQGNTVFHILVLHQNKSMACKMYDFLAAIIPKKQLSYLETITNND 214

  Fly   315 -LTPLTLAAKLGRVEMFFHVMSIEREIYWQLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVF 378
             :||..|||:.|.|:||.:.:...|......|.:....|.|..||:.::..      ||::.:..
 Frog   215 GMTPFKLAAQQGDVQMFEYFIKKRRHTILSFGPLGSTLYDLTGIDSWDDRL------SVIDIICT 273

  Fly   379 GDKLEHLELLDGVVI-DLLKTKWDTFCKSRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGA 442
            .:......||:...: :||..||..|    .||.|.:..::::  :::.||
 Frog   274 SNNNAARNLLEITPLKELLHYKWTAF----GYKYFLLCTIFYI--MYTVIL-------------- 318

  Fly   443 NSTTAKSDLYRQNGSDSYHLHSKRATMTTEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNL 507
                                     |:...|:.....||  |...:.......:|:|      ..
 Frog   319 -------------------------TLCCLYRPIMHTFT--YQDGKGNTRKPLYEAY------QT 350

  Fly   508 ESDLAKLRIMAELLNFVGAILYLLVALREARFLGLKMFIENLMT-APSRVMFLFSCALMMTIPWL 571
            .:|.  ||:..|::..||.||.|:..:.:....|.|.|..|.:| .|..|:.|.....::.:..|
 Frog   351 RNDY--LRLSGEIIVVVGGILCLVSEILQFVRKGTKHFFGNTVTGGPFHVILLLYACFIIAVVIL 413

  Fly   572 RVSCLTEIDDHVTVVIMLTTAPYF---LFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMG 633
            |...    .|..|:::.|.....:   ::|.|||:.:||..:||.:||:||||:|..:.:..::|
 Frog   414 RFLS----SDGETIMMSLALISAWCNVIYFARGFRLLGPLCIMIQKMVLGDLLKFCILLIAVLIG 474

  Fly   634 FSQAFYIIFLTFDNPSSPEDQDAESNPMPS---------------PMESIVAMFLMSLTNFGDYY 683
            |:.||.:.|...:..:.|     ..|..|.               |:.:.:.|..|.|
 Frog   475 FAAAFNVHFQAMNTTAVP-----SFNGFPDITFTLFQLMMGLDSLPLPANIVMPKMIL------- 527

  Fly   684 GAMVSTQHEYEAKILFFLFMVIVSVLLVNMLIAMMGNTYQKIAEIRNE-WQRQWARIVLVVERSV 747
                         :|:.::|....|||||:|||:|.:|:.::...|.. |:.|.|...:::|||:
 Frog   528 -------------VLYIVYMFFGFVLLVNLLIALMTHTHFRVTNDRTTLWRAQVAATTIMLERSI 579

  Fly   748 P 748
            |
 Frog   580 P 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nan	NP_001261833.1	TRPV	131..748	CDD:454755	162/648 (25%)
		ANK repeat	138..174	CDD:293786	10/35 (29%)
		ANK repeat	179..229	CDD:293786	17/50 (34%)
		ANK repeat	231..278	CDD:293786	11/46 (24%)
		ANK repeat	280..311	CDD:293786	10/37 (27%)
LOC105947301	XP_017949519.2	TRPV	21..609	CDD:454755	163/651 (25%)
		ANK repeat	53..88	CDD:293786	10/37 (27%)
		ANK repeat	91..122	CDD:293786	14/30 (47%)
		ANK repeat	133..169	CDD:293786	11/46 (24%)