Protein Alignment nan and LOC100494817

DIOPT Version :10

• Sequence 1: NP_001261833.1
• Gene: nan / 39571
• FlyBaseID: FBgn0036414
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: XP_017950396.2
• Gene: LOC100494817 / 100494817
• XenbaseID: XB-GENE-29082407
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 627
• Identity: 157/627 - (25%)
• Similarity: 260/627 - (41%)
• Gaps: 165/627 - (26%)

  Fly   180 GESVLHIAIVNEDPAMVKYLLDANADVQERCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDGY 244
            |::.|||||.......|:.|:...|||..:..|.|...:|.                     .|.
 Frog    10 GQTALHIAIERRCKDYVELLVQKGADVHAQAKGRFFQPKDE---------------------GGC 53

  Fly   245 VYWGEYPLSFAACLSQEECFRLV---LARGADPDFQDTNGNTVLHMLV-IYEKIE--------MF 297
            .|:||.|||.|||..|::....:   :...||...||:.||||||.|| |.:..|        |:
 Frog    54 FYFGELPLSLAACTKQDDIVDYLTENVYNKADLCRQDSRGNTVLHALVAIADNTEETTTFVTKMY 118

  Fly   298 D----VGYEVGTNIHIKNIQN---LTPLTLAAKLGRVEMFFHVMSIE-------------REIYW 342
            |    ...::.....::.|.|   ::||.:||:||::::|.|::.:|             |:  |
 Frog   119 DRLVVKCAKLNKECRLETILNNDKMSPLMMAAQLGKIDIFQHIIQLEIKDEEAQHLSRKFRD--W 181

  Fly   343 QLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVFGD--KLEHLELLDGVVIDLLKTKWDTFCK 405
            ..|.:..:.|.|..:||.  |.|    ||||..:|:..  |..|..|....:.:|||.||..|..
 Frog   182 NYGPLHSSLYDLATLDTY--EDG----DSVLEILVYKSTAKNRHEMLAVEPINELLKEKWKKFGA 240

  Fly   406 SRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGANSTTAKSDLYRQNGSDSYHLHSKRATMT 470
            ..||..|  ||..||:.:|:.|
 Frog   241 VFFYLSF--FAYLFLMIIFTLI------------------------------------------- 260

  Fly   471 TEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNLESDLAKLRIMAELLNFVGAILYLLVALR 535
                       .||.|.|            ..|.....:....||::.|::..:..|::|:..::
 Frog   261 -----------SYYRPME------------GTPPYPYRTTTDHLRLVGEIIILLTGIVFLIGNMK 302

  Fly   536 EARFLGLKMF--IENLMT--APSRVMFLFSCALMMTIPWLRVSCLTEIDDHVTVVIMLTTAPYF- 595
            :   |.:|.:  :.:|.|  ....:.|::|..:::|    ....|..|:.::.|:::.....:.
 Frog   303 D---LIMKKYPGVYSLFTDGCFQLLNFIYSVLVIIT----ATLYLAGIEAYLAVMVIALVLGWIN 360

  Fly   596 -LFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMGFSQAFYIIFLTFDNP--------SSP 651
             |:|.||.|..|.:.||:.:::..||.||:.:||:|::|::.|...:.    ||        ...
 Frog   361 ALYFTRGLKLTGMYSVMLQKVLFKDLFRFLLVYLLFMVGYASALVSLL----NPCTNEMICNDGQ 421

  Fly   652 EDQDAESNPMPSPMESIVAMFLMSLT---NFGDYYGAMVSTQHEYEAK--ILFFLFMVIVSVLLV 711
            |:.....||......:.:::.|...|   ..||   ..|.:..:|.|.  :|...:::|..|||:
 Frog   422 ENCTVSENPSCQHSTTFISLLLNLFTLTIGMGD---LEVISHAKYPAVFIVLLVTYLIITFVLLL 483

  Fly   712 NMLIAMMGNTYQKIA-EIRNEWQRQWARIVLVVERSVPPAER 752
            |||||:||.|..::: |.:..||.|||..:|.:||.:|...|
 Frog   484 NMLIALMGETVGEVSKESKQIWQLQWATTILDIERYLPACMR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nan	NP_001261833.1	TRPV	131..748	CDD:454755	155/621 (25%)
		ANK repeat	138..174	CDD:293786
		ANK repeat	179..229	CDD:293786	14/48 (29%)
		ANK repeat	231..278	CDD:293786	13/49 (27%)
		ANK repeat	280..311	CDD:293786	12/43 (28%)
LOC100494817	XP_017950396.2	ANK repeat	9..40	CDD:293786	11/29 (38%)
		TRPV	10..571	CDD:454755	157/627 (25%)
		ANK repeat	56..90	CDD:293786	11/33 (33%)
		ANK repeat	92..131	CDD:293786	12/38 (32%)