DRSC/TRiP Functional Genomics Resources

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Protein Alignment D and Sox11

DIOPT Version :9

Sequence 1:NP_001261830.1 Gene:D / 39570 FlyBaseID:FBgn0000411 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_445801.1 Gene:Sox11 / 84046 RGDID:69351 Length:395 Species:Rattus norvegicus


Alignment Length:325 Identity:103/325 - (31%)
Similarity:137/325 - (42%) Gaps:108/325 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   140 GHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMK 204
            ||||||||||||||:::||:|.:.:|.|||:|||||||..||:|.:|||.|||.||:|||..||.
  Rat    47 GHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMA 111

  Fly   205 EHPDYKYRPRRKPKNPLTAGPQGGLQMQAGGMGQQKLGAGPG------------AGAG-GYNP-- 254
            ::||||||||:|||....|.|..|........| .|...|||            |||| ...|  
  Rat   112 DYPDYKYRPRKKPKTDPAAKPSAGQSPDKSAAG-AKAAKGPGKKCAKLKAPAGKAGAGKAAQPGD 175

  Fly   255 ------------------------------------------FHQLPPYFAPSHHLDQGYPVPYF 277
                                                      .|.|||   |:    |..|....
  Rat   176 CGAGKAAKCVFLDDDDEEDDEDDELQLRPKPDADDDDDEPAHSHLLPP---PA----QQQPPQLL 233

  Fly   278 GGFDPLALSKLHQSQAAAAAAVNNQG----------------------QQQGQAPPQLPPTS--- 317
            ..:   :::|:..|...::||.:.:|                      ||...|||.|.|.|   
  Rat   234 RRY---SVAKVPASPTLSSAAESPEGASLYDEVRAGGRLYYSFKNITKQQPPPAPPALSPASSRC 295

  Fly   318 -LSSFYSGIYSGISAP---------SLYAAHSANAAGLYPSSSTSSPGSSPGTITPNGMDGSMDS 372
             .:|..||..||..|.         ||..:..|::|...|..:     .:.|.::.:.:|..:||
  Rat   296 VSTSSSSGSSSGSGAEDADDLMFDLSLNFSQGAHSACEQPLGA-----GAAGNLSLSLVDKDLDS 355

  Fly   373  372
              Rat   356  355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DNP_001261830.1 SOX-TCF_HMG-box 141..212 CDD:238684 47/70 (67%)
Sox11NP_445801.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
SOX-TCF_HMG-box 48..119 CDD:238684 47/70 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..258 36/154 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 276..312 14/35 (40%)
Required for transcriptional activation activity and synergistic coactivation of transcriptional activity with POU3F2. /evidence=ECO:0000250|UniProtKB:Q7M6Y2 363..395
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.910

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