Protein Alignment D and SOX7

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_113627.1
• Gene: SOX7 / 83595
• HGNCID: 18196
• Length: 388
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 93/293 - (31%)
• Similarity: 129/293 - (44%)
• Gaps: 91/293 - (31%)

  Fly   137 GQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRAL 201
            |.|..|:|||||||||::.:|:::|..||.:||:|:||.||..||.|..|:|||::|||:|||..
Human    40 GSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104

  Fly   202 HMKEHPDYKYRPRRK---------------------PKNPL---TAGPQGGLQMQAGGMGQQKLG 242
            ||:::|:||||||||                     .:|.|   .:|.:|.|. :....|:...|
Human   105 HMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALG-EKEDRGEYSPG 168

  Fly   243 A-----------GPGAGAGGYNPFH--------QLPPYFAPSHHL-------------DQGYP-- 273
            .           ||..|.||..|..        ..||..:|...|             :.|:|
Human   169 TALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRR 233

  Fly   274 VPYFGG--FDP-LALSKLHQSQAAAAAAVNNQGQQQGQAP--------PQLPPTSLSSFYSGIYS 327
            :|:..|  :.| .|.|.||.|....:.|:       ||:|        |..||:  .::||
Human   234 IPHLPGHPYSPEYAPSPLHCSHPLGSLAL-------GQSPGVSMMSPVPGCPPS--PAYYS---- 285

  Fly   328 GISAPSLY-AAHSANAAGLYPSSSTSSPGSSPG 359
                |:.| ..||...|.|   ...|.|...||
Human   286 ----PATYHPLHSNLQAHL---GQLSPPPEHPG 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	39/70 (56%)
SOX7	NP_113627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..46		2/5 (40%)
		SOX-TCF_HMG-box	44..115	CDD:238684	39/70 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..197		13/57 (23%)
		Sox_C_TAD	198..386	CDD:288887	33/134 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940