Protein Alignment D and sox18

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_017209261.1
• Gene: sox18 / 797246
• ZFINID: ZDB-GENE-080725-1
• Length: 431
• Species: Danio rerio
• Alignment Length: 401
• Identity: 112/401 - (27%)
• Similarity: 159/401 - (39%)
• Gaps: 108/401 - (26%)

  Fly    43 LHYSQSLAAMGGS--PNGPAGQGVNGSSG------MGHHMSSHMTPHHMHQAVSAQQTLSPNSSI 99
            ::.|:|......|  |:..|.:|..|:|.      .||......|........|..:|:|..:
Zfish     1 MNISESSCCQEASSQPSQVAERGTWGASSSTPGPERGHGFDRSRTTELAPVPGSGTRTVSRTA-- 63

  Fly   100 GSAGSLGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDN 164
             :....||..|.......|.||.|           ..|.|..|:|||||||||::.:|:::|..|
Zfish    64 -AEARTGSPDSTRPGALTLGSSEG-----------KSGGESRIRRPMNAFMVWAKDERKRLAIQN 116

  Fly   165 PKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRK--PKNPLTAGPQG 227
            |.:||:.:||.||..||.|:..:||||::||:|||..|:::||:||||||||  ||......|
Zfish   117 PDLHNAVLSKMLGQSWKALSTLDKRPFVEEAERLRLQHLQDHPNYKYRPRRKKQPKKMKRVEP-- 179

  Fly   228 GLQMQAGGMGQQKLGAGPGAGAGGYNP----FHQLPP--YFAPSH-----HLDQ-GYPVPYF--- 277
            ||.:|....|      |||   ..|:|    .|.|||  :|...|     .|:. |.|.|..
Zfish   180 GLLLQGLAHG------GPG---DAYSPHRHAHHLLPPLGHFRDLHPSGAPELESFGLPTPEMSPL 235

  Fly   278 -----GGFDPLALSKLHQSQAAAAAAVN---NQGQQQGQAPPQ---------------------- 312
                 ||.|.:......|.....::.:|   :...|.|..|..
Zfish   236 DVLEEGGGDSVFFPPHMQEDVGLSSWINYHQHPNHQPGHHPHHNSHNLQHSHPHLNQKSPLACLP 300

  Fly   313 ---------------------LPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGS 356
                                 ||.:|.:.:|..|| |.|.|.  .|.:::...|.|...||:...
Zfish   301 LQEKCLVVESPNPGGLYPNMTLPESSKAGYYGQIY-GSSQPQ--PAFTSHLGQLSPPPETSAVAQ 362

  Fly   357 SPGTITPNGMD 367
                :.|..:|
Zfish   363 ----VAPPSLD 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	37/70 (53%)
sox18	XP_017209261.1	SOX-TCF_HMG-box	93..164	CDD:238684	37/70 (53%)
		Sox_C_TAD	207..429	CDD:288887	31/170 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940