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Protein Alignment D and SOX3

DIOPT Version :9

Sequence 1:	NP_001261830.1	Gene:	D / 39570	FlyBaseID:	FBgn0000411	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_005625.2	Gene:	SOX3 / 6658	HGNCID:	11199	Length:	446	Species:	Homo sapiens

Alignment Length:	401	Identity:	139/401 - (34%)
Similarity:	179/401 - (44%)	Gaps:	95/401 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SQSL----AAMGGSPNGPAGQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQTLSP-NSSIGSAGSL 105
            ||.|    |...|:|:.||             ..:|:.|.....::...:..:| .:...:||:.
Human    47 SQGLFTVAAPAPGAPSPPA-------------TLAHLLPAPAMYSLLETELKNPVGTPTQAAGTG 98

  Fly   106 GSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEG----HIKRPMNAFMVWSRLQRRQIAKDNPK 166
            |..:..|:..|..|::.|..|.|..|...|.|..|    .:||||||||||||.|||::|.:|||
Human    99 GPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPK 163

  Fly   167 MHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKN-------PLTAG 224
            ||||||||||||:||||.::||||||||||||||:||||:||||||||||.|.       .|.:|
Human   164 MHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSG 228

  Fly   225 --PQGGLQMQAGGMGQQKLGAGP-GAGA-------------GGYNPFHQL--------------P 259
              |.|.....|.........:.| |.|.             |.|:...:.              |
Human   229 LLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPP 293

  Fly   260 PYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAAVNNQGQQQGQAPPQLPPTSLSSFYSG 324
            |...|.|..|.. .:.|.....|.|.|  :.:.||||||.:..|   |.||      |.::..:.
Human   294 PALPPMHRYDMA-GLQYSPMMPPGAQS--YMNVAAAAAAASGYG---GMAP------SATAAAAA 346

  Fly   325 IYSGISAPSLYAAHSANAAGLYPSSST--SSPGSSPGTIT-------------------PNGMDG 368
            .|....|.:..||.:|.|..|.|..|.  |.|.|.|..|.                   |.|.|.
Human   347 AYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDA 411

  Fly   369 SMDSALRRPVP 379
            : |:|  .|:|
Human   412 A-DAA--SPLP 419

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.