Protein Alignment D and sox9

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001016853.1
• Gene: sox9 / 549607
• XenbaseID: XB-GENE-1034769
• Length: 482
• Species: Xenopus tropicalis
• Alignment Length: 391
• Identity: 102/391 - (26%)
• Similarity: 139/391 - (35%)
• Gaps: 166/391 - (42%)

  Fly   141 HIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKE 205
            |:||||||||||::..||::|...|.:||:|:||.||..|:||.|.|||||::||:|||..|.|:
 Frog   104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRIQHKKD 168

  Fly   206 HPDYKYRPRRK------------------------------------------------------ 216
            ||||||:|||:
 Frog   169 HPDYKYQPRRRKSVKNGQSEQEDGAEQTHISPNAIFKALQADSPHSASSMSEVHSPGEHSGQSQG 233

  Fly   217 ----PKNPLTAGPQGGLQMQAGGMGQQKLGAGP------GAGAG-------------GYNPFHQ- 257
                |..|.|....|...::..|...|:.|..|      ....|             ..|.|.|
 Frog   234 PPTPPTTPKTDVQPGKPDLKREGRPLQESGRQPPHIDFRDVDIGELSSEVISTIETFDVNEFDQY 298

  Fly   258 LPPYFAPSHHLDQGYP------VPYFG------------GFDPLALSKLHQSQAA-------AAA 297
            |||         .|:|      .||.|            |..|..:||..|.|..       :.:
 Frog   299 LPP---------NGHPGVGSTQAPYTGSYGINSTPSATPGAGPAWMSKQQQQQQQQPQPPQHSLS 354

  Fly   298 AVNNQ---------------------GQQQGQAPPQLPPTSLSSF----YSGIYSGIS------- 330
            .:|::                     .|||..:|.||   :.|||    ||..|..|:
 Frog   355 TINSEQSQSQQRTHIKTEQLSPSHYSDQQQQHSPQQL---NYSSFNLQHYSSSYPTITRAQYDYT 416

  Fly   331 ----APSLYAAHSANAAGLY---------------PSSSTSSPGSSPGTITPNGMDGSMDSALRR 376
                :.|.|:..|...:|||               |.:.|:...|.|.|.:|...:..:.:.|.|
 Frog   417 EHQGSNSYYSHASGQNSGLYSNFSYMNPSQRPMYTPIADTTGVPSIPQTHSPQHWEQPVYTQLTR 481

  Fly   377 P 377
            |
 Frog   482 P 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	43/70 (61%)
sox9	NP_001016853.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66
		Sox_N	22..94	CDD:403592
		Dimerization (DIM). /evidence=ECO:0000250|UniProtKB:P48436	63..103
		PQA. /evidence=ECO:0000250|UniProtKB:P48436	63..103
		SOX-TCF_HMG-box	104..174	CDD:238684	42/69 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..274		22/113 (19%)
		Transactivation domain (TAM). /evidence=ECO:0000250|UniProtKB:P48436	224..308		17/92 (18%)
		9aaTAD 1. /evidence=ECO:0000250|UniProtKB:P48436	276..285		1/8 (13%)
		9aaTAD 2. /evidence=ECO:0000250|UniProtKB:P48436	291..299		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..395		23/111 (21%)
		Transactivation domain (TAC). /evidence=ECO:0000250|UniProtKB:P48436	366..482		26/118 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..482		7/33 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910