Protein Alignment D and Sox2

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001102651.1
• Gene: Sox2 / 499593
• RGDID: 1565646
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 273
• Identity: 112/273 - (41%)
• Similarity: 141/273 - (51%)
• Gaps: 43/273 - (15%)

  Fly   106 GSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEG---HIKRPMNAFMVWSRLQRRQIAKDNPKM 167
            |.|.:.|..|.|.|:::.         ||...|:.   .:||||||||||||.|||::|::||||
  Rat    13 GPQQASGGGGGGGNATAA---------ATGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKM 68

  Fly   168 HNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGP---QGGL 229
            ||||||||||||||||:|:||||||||||||||||||||||||||||||.|..:....   .|||
  Rat    69 HNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGL 133

  Fly   230 QMQAGGMGQQKLGAGPGAGAG---GYNPFHQLPPYFAPSHHLDQ---GYPV-PYFGGFDPLALSK 287
            ....|......:|.|.|.|||   ..:.:..:..:...|:.:.|   |||. |.........:..
  Rat   134 LAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQEQLGYPQHPGLNAHGAAQMQP 198

  Fly   288 LHQSQAAAA---AAVNNQGQQQGQAPPQLPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYPSS 349
            :|:...:|.   :..::|....|.      ||     ||..||....|.:       |.|...|.
  Rat   199 MHRYDVSALQYNSMTSSQTYMNGS------PT-----YSMSYSQQGTPGM-------ALGSMGSV 245

  Fly   350 STSSPGSSPGTIT 362
            ..|...|||..:|
  Rat   246 VKSEASSSPPVVT 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	61/70 (87%)
Sox2	NP_001102651.1	SOX-TCF_HMG-box	42..113	CDD:238684	61/70 (87%)
		SOXp	112..202	CDD:403523	24/89 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.870