Protein Alignment D and Cic

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001359008.1
• Gene: Cic / 308435
• RGDID: 1310706
• Length: 2513
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 111/511 - (21%)
• Similarity: 154/511 - (30%)
• Gaps: 210/511 - (41%)

  Fly    53 GGSPNGPAGQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSG 117
            |..|..|.|.....|.|.|        |......|...::|.|.:...:.|..| :..|.|
  Rat   997 GADPGRPPGATCPESPGPG--------PPLTLGGVDPGKSLPPTTEEEAPGPPG-EPRLDS---- 1048

  Fly   118 LNSSSGHQSAGMH------SLATSPG----------------------------QEGHIKRPMNA 148
             .:.|.|..|.:.      .|...||                            ::.||:|||||
  Rat  1049 -ETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNA 1112

  Fly   149 FMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKY-- 211
            ||::|:..|..:.:.:|...|..:||.||..|..|...||:.:.|.|.:::..|.|.|||:|:
  Rat  1113 FMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCN 1177

  Fly   212 RPRRKPKN---PLTAGPQGGLQ------------MQAGGMGQQKLGA-----------GPGAGAG 250
            :.|:|..:   |.:.|..||.:            ..|.|:..:.|.|           .||:|..
  Rat  1178 KDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSAAAQTLLSSDTKAPGSGPC 1242

  Fly   251 GYNPFHQL-------PPYFAPS--HHLDQG-----------------------YPVPYFG----- 278
            |....|.:       |..|:.|  |.||.|                       .|.|.:|
  Rat  1243 GAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPTSFSGPKPSPQYGAPGSF 1307

  Fly   279 ------------GFDPLALSKLHQSQAAAAAAV-------------------------------- 299
                        |..||..|:..:||.||:..:
  Rat  1308 AAPGEGGNLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLK 1372

  Fly   300 -------NNQGQQQGQAP--------------------------------PQLPPTSLSSFYSGI 325
                   :..|...|:.|                                |..||.:.|..|...
  Rat  1373 CKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFSKGYGPT 1437

  Fly   326 YSGISAPSLYAAHSANAAGLYPSSSTS-SPGSSPGTI-TPNGMDGSMDSALRRPVP 379
            .|..|:|          |....|.||| |.||  ||. |.....||....||.|.|
  Rat  1438 PSSSSSP----------ASTSVSVSTSFSLGS--GTFKTQESGQGSTAVPLRPPPP 1481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	29/72 (40%)
Cic	NP_001359008.1	DUF4819	252..346	CDD:374357
		PHA03247	<749..1060	CDD:223021	18/76 (24%)
		NHP6B	<1077..1221	CDD:227935	37/143 (26%)
		SOX-TCF_HMG-box	1105..1176	CDD:238684	29/70 (41%)
		PRK07003	<1552..>1694	CDD:235906
		PHA03247	<1638..2180	CDD:223021

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910