Protein Alignment D and Meiosin

DIOPT Version :10

• Sequence 1: NP_524066.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001357740.1
• Gene: Meiosin / 243866
• MGIID: 3647482
• Length: 589
• Species: Mus musculus
• Alignment Length: 208
• Identity: 44/208 - (21%)
• Similarity: 70/208 - (33%)
• Gaps: 85/208 - (40%)

  Fly    55 SPNGPAGQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQ---TLSPN----SSIGSAG--------- 103
            |..||.|                  |.:...:||...   :||.|    |:.||:.
Mouse   352 SSEGPTG------------------PPNFQSSVSLDHCYLSLSENVKVLSNCGSSSESTDTESLW 398

  Fly   104 ------------------SLGSQSSL-GSNGSGLNSSSGH----------QSAGM---------- 129
                              ||...|.| .:|..||.:||..          ||:|:
Mouse   399 GQEEVRGVATYPRRTGVFSLAQPSVLQQANPEGLQTSSDEDRDYTWTPTGQSSGLPVASKKIKKV 463

  Fly   130 ----------HSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLA 184
                      .|....|||..  |:.:|.|:::.|:.|:|..:..|...::..:|.|...|:.:.
Mouse   464 QASQGPVKPKDSRKACPGQVK--KKCVNGFIMFCRMNRKQYIRACPGTASTAATKDLAQLWRGMT 526

  Fly   185 ESEKRPFIDEAKR 197
            ..||:|:..:|:|
Mouse   527 LEEKKPYCTKARR 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_524066.1	HMG-box_SoxB	140..219	CDD:438790	15/58 (26%)
Meiosin	NP_001357740.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	14..27
		bHLH_SF	24..73	CDD:469605
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	28..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..191
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..363		5/28 (18%)
		NHP6B	416..>539	CDD:227935	30/124 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..457		10/34 (29%)
		HMG-box_BHMG1	484..549	CDD:438793	15/58 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	544..566