DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment D and Sox30

DIOPT Version :9

Sequence 1:	NP_001261830.1	Gene:	D / 39570	FlyBaseID:	FBgn0000411	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_775560.1	Gene:	Sox30 / 214105	MGIID:	1341157	Length:	782	Species:	Mus musculus

Alignment Length:	275	Identity:	78/275 - (28%)
Similarity:	121/275 - (44%)	Gaps:	73/275 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 AGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPF 191
            ||:.....|..:.||:||||||||||:|:.|..:||.||..:|:|||.:||.||..|:|.:|:|:
Mouse   351 AGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPY 415

  Fly   192 IDEAKRLRALHMKEHPDYKYRPR--RKPKNPLTAGPQGGLQMQAGGMGQQKLGAGPGAGAGGYNP 254
            .|||::::..|.:|.|.:.|:||  ::.:.||:      :.....|..|..:...|..
Mouse   416 YDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLS------VSNVFSGTTQNIISTNPTT------- 467

  Fly   255 FHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAAVNNQGQQQGQAPP--QLP--- 314
               :.||.:|::.:    .:|                     ...|......|:|||  |||
Mouse   468 ---IYPYRSPTYSV----VIP---------------------GLQNTITHPVGEAPPAIQLPTPA 504

  Fly   315 ---PTSLSSFYSGIYS----GISAPSL----------YAAHSANAAGLYPSSSTSSPGSSPGTIT 362
               |:.::.|...:.|    .:..|||          ::..|.......||.|:.|...|    |
Mouse   505 VQRPSPITLFQPSVSSTGPVAVPPPSLTPRPSLPPQRFSGPSQTDIHRLPSGSSRSVKRS----T 565

  Fly   363 PNGMDGSMDSALRRP 377
            |    ||::|..|.|
Mouse   566 P----GSLESTTRIP 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	35/70 (50%)
Sox30	NP_775560.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..117
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	139..226
		SOX-TCF_HMG-box	365..435	CDD:238684	35/69 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	501..604		20/84 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..724
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	756..782
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810