DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment D and Sox5

DIOPT Version :9

Sequence 1:	NP_001261830.1	Gene:	D / 39570	FlyBaseID:	FBgn0000411	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_006506994.1	Gene:	Sox5 / 20678	MGIID:	98367	Length:	792	Species:	Mus musculus

Alignment Length:	236	Identity:	77/236 - (32%)
Similarity:	104/236 - (44%)	Gaps:	63/236 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SIGSAGSLGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAK 162
            |.||||...|:....|.|.|.|                   |.||||||||||||::.:||:|.:
Mouse   560 SDGSAGVSESRIYRESRGRGSN-------------------EPHIKRPMNAFMVWAKDERRKILQ 605

  Fly   163 DNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQG 227
            ..|.||||.|||.||:.||.:...||:|:.:|..||...|::::|||||:||  ||.....   .
Mouse   606 AFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR--PKRTCLV---D 665

  Fly   228 GLQMQAG-----------------GMGQQKLGAGPGAGAGGYNP----FHQLPPYFAPSHHL--- 268
            |.:::.|                 .:|||  ...|.|.||...|    ...:|....||.|.
Mouse   666 GKKLRIGEYKAIMRNRRQEMRQYFNVGQQ--AQIPIATAGVVYPSAIAMAGMPSPHLPSEHSSVS 728

  Fly   269 ---DQGYPV--PYFG--GFDPLALSKLHQSQAAAAAAVNNQ 302
               :.|.||  ..:|  |.:|      |..:...|..:|.:
Mouse   729 SSPEPGMPVIQSTYGAKGEEP------HIKEEIQAEDINGE 763

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	38/70 (54%)
Sox5	XP_006506994.1	SOX-TCF_HMG-box	584..655	CDD:238684	38/70 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900