Protein Alignment D and Sox3

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_033263.2
• Gene: Sox3 / 20675
• MGIID: 98365
• Length: 450
• Species: Mus musculus
• Alignment Length: 443
• Identity: 139/443 - (31%)
• Similarity: 187/443 - (42%)
• Gaps: 123/443 - (27%)

  Fly    22 DYA--PQSQLQLSPGMDMDIKRVLHYSQS--------LAAMGGSPNGPAGQGVNGSSGMGHHMSS 76
            |:|  |.:.|...|  ::..:|.|..:.:        .|...|:|:.||             ..:
Mouse    19 DFARSPSASLPFPP--ELPARRPLSTTPTESPGLFTVAAPAPGAPSPPA-------------TLA 68

  Fly    77 HMTPHHMHQAVSAQQTLSP------------NSSIGSAGSLGSQSSLGSNGSGLNSSSGHQSAGM 129
            |:.|.....::...:..:|            .::.|:||..|:..:.|:|..  |..||..:.|.
Mouse    69 HLLPAPAMYSLLETELKNPVGPPTPAAGTGVPAAPGAAGKSGANPAGGANAG--NGGSGGANGGG 131

  Fly   130 HSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDE 194
            .........:..:||||||||||||.|||::|.:|||||||||||||||:||||.::||||||||
Mouse   132 GGGGGGGSDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDE 196

  Fly   195 AKRLRALHMKEHPDYKYRPRRKPKNPLTAGP---QGGL----------QMQAGGMGQQKLGAGP- 245
            ||||||:||||:||||||||||.|..|....   .|||          ...|.......:|.|.
Mouse   197 AKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGGLLPPGAAAAAAAAAAAAAASSPVGVGQR 261

  Fly   246 --------GAGAGGYNPFHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQ------------ 290
                    |...|.|:...:...|..|.   ....|.|      |.||.::|:
Mouse   262 LDTYTHVNGWANGAYSLVQEQLGYAQPP---SMSSPPP------PPALPQMHRYDMAGLQYSPMM 317

  Fly   291 --------SQAAAAAAVNNQGQQQGQAPPQLPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYP 347
                    :.||||||.:..|   |.||      |.::..:..|....|.:..||.:|.|..|.|
Mouse   318 PPGAQSYMNAAAAAAAASGYG---GMAP------SAAAAAAAAYGQQPATAAAAAAAAAAMSLGP 373

  Fly   348 SSST--SSPGSSPGTIT-------------------PNGMDGSMDSALRRPVP 379
            ..|.  |.|.|.|..|.                   |.|.|.: |:|  .|:|
Mouse   374 MGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAA-DAA--SPLP 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	57/70 (81%)
Sox3	NP_033263.2	SOX-TCF_HMG-box	143..214	CDD:238684	57/70 (81%)
		SOXp	213..306	CDD:289133	25/101 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I4213
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.920