Protein Alignment D and Sox17

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001276393.1
• Gene: Sox17 / 20671
• MGIID: 107543
• Length: 419
• Species: Mus musculus
• Alignment Length: 367
• Identity: 106/367 - (28%)
• Similarity: 156/367 - (42%)
• Gaps: 99/367 - (26%)

  Fly    67 SSGMGHHMSSHMTPHHMHQAVSA-------QQTLSPNSSIGSAGSLGSQSSLGSNGSGLNSSSGH 124
            |...|:.......|.....||.|       .::|||...:...|.:     :.|:|:.. .:||.
Mouse     3 SPDAGYASDDQSQPRSAQPAVMAGLGPCPWAESLSPLGDVKVKGEV-----VASSGAPA-GTSGR 61

  Fly   125 QSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKR 189
            ..|           |..|:|||||||||::.:|:::|:.||.:||:|:||.||..||.|..:|||
Mouse    62 AKA-----------ESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKR 115

  Fly   190 PFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGG-----LQMQAGGMGQQ-----KLGAG 244
            ||::||:|||..||::||:|||||||:.:.......:||     ::.|||.:|.:     ..|.|
Mouse   116 PFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRMKRVEGGFLHALVEPQAGALGPEGGRVAMDGLG 180

  Fly   245 -----PGAGAGGYNPFHQLPPYFAP---SHHLD-QGYPVPYFGGF-----DPLALSKLHQSQAAA 295
                 ||..||        ||..:|   .|:.| ||...|...|:     |...|..:.|..|..
Mouse   181 LPFPEPGYPAG--------PPLMSPHMGPHYRDCQGLGAPALDGYPLPTPDTSPLDGVEQDPAFF 237

  Fly   296 AA--------------------AVNNQ---------GQQQGQAPPQL--PPTSLSSFYSGIYSGI 329
            ||                    ||:.:         ....|.|.|.:  ||::|..:    |..:
Mouse   238 AAPLPGDCPAAGTYTYAPVSDYAVSVEPPAGPMRVGPDPSGPAMPGILAPPSALHLY----YGAM 298

  Fly   330 SAPSLYAA---HSANAAGLYPSS-----STSSPGSSPGTITP 363
            .:|:..|.   |:.....|.|.:     ....|...||..:|
Mouse   299 GSPAASAGRGFHAQPQQPLQPQAPPPPPQQQHPAHGPGQPSP 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	40/70 (57%)
Sox17	NP_001276393.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		6/23 (26%)
		SOX-TCF_HMG-box	67..138	CDD:238684	40/70 (57%)
		Sox17_18_mid	203..253	CDD:403331	11/49 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..356		8/38 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940