Protein Alignment D and Sox15

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_033261.1
• Gene: Sox15 / 20670
• MGIID: 98363
• Length: 231
• Species: Mus musculus
• Alignment Length: 246
• Identity: 99/246 - (40%)
• Similarity: 127/246 - (51%)
• Gaps: 52/246 - (21%)

  Fly   118 LNSSSGHQSAGMHSLAT---------------SPGQEG-----HIKRPMNAFMVWSRLQRRQIAK 162
            |.|||..::..:|..|:               |||..|     .:|||||||||||.:||||:|:
Mouse     3 LTSSSQAETWSLHPRASTASLPLGPQEQEAGGSPGASGGLPLEKVKRPMNAFMVWSSVQRRQMAQ 67

  Fly   163 DNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQG 227
            .|||||||||||||||:||||.:.|||||::|||||||.|::::||||||||||.||..|....
Mouse    68 QNPKMHNSEISKRLGAQWKLLGDEEKRPFVEEAKRLRARHLRDYPDYKYRPRRKSKNSSTGSVP- 131

  Fly   228 GLQMQAGGM--GQQKLGAG----PGAGAGGYNPFH----QLPPYFAPSHHLDQGYPVP-YFGGFD 281
             ...:.||:  |....|.|    .|:...||.|.:    .||..:..||...:. |:| .|...|
Mouse   132 -FSQEGGGLACGGSHWGPGYTTTQGSRGFGYQPPNYSTAYLPGSYTSSHCRPEA-PLPCTFPQSD 194

  Fly   282 PLALSKLHQSQAAAAAAVNNQGQQQGQAPPQLPPTSLSSFYSGIYSGISAP 332
            |                 ..||:.:....|.|.|.| |:.|:...:|...|
Mouse   195 P-----------------RLQGELRPSFSPYLSPDS-STPYNTSLAGAPMP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	52/70 (74%)
Sox15	NP_033261.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		10/41 (24%)
		Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000269|PubMed:16759287	1..45		10/41 (24%)
		SOX-TCF_HMG-box	46..117	CDD:238684	52/70 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..136		13/26 (50%)
		Interaction with FHL3. /evidence=ECO:0000269|PubMed:17363903	136..181		13/44 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..231		14/60 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870