Protein Alignment D and sox-3

DIOPT Version :9

• Sequence 1: NP_001261830.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_510439.1
• Gene: sox-3 / 185534
• WormBaseID: WBGene00004950
• Length: 212
• Species: Caenorhabditis elegans
• Alignment Length: 245
• Identity: 100/245 - (40%)
• Similarity: 119/245 - (48%)
• Gaps: 73/245 - (29%)

  Fly    90 QQTLSPNSSIGSAGS-LGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWS 153
            :.|.|.:|.:...|| :..|:||                            .|:|||||||||||
 Worm    23 EDTTSVSSGLSPPGSPVDLQNSL----------------------------DHVKRPMNAFMVWS 59

  Fly   154 RLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPK 218
            |.|||::|:|||||||||||||||||||.|:|.||||||||||||||||||||||||||||||||
 Worm    60 RGQRRKMAQDNPKMHNSEISKRLGAEWKQLSEQEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPK 124

  Fly   219 NP-LTAGPQGGLQMQAGGMGQQKLGAGPGAGAGGYNPFHQLPPY----------FAPSHHLDQGY 272
            :. |...|:..:.|..                        :||.          ...:|.|.|.|
 Worm   125 SSNLKQQPRLNIAMPT------------------------IPPQSLFNYSTAFDSLKTHDLSQYY 165

  Fly   273 ------PVPYFGGFDPLALSKLHQSQAAAAAAVNNQGQQQGQAPPQLPPT 316
                  ||.....:.|..:...:..||||.||.:   |......|..|.|
 Worm   166 SSFFQSPVLSGSTYAPYNMMAAYARQAAAVAAAS---QVSASTTPTAPAT 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D	NP_001261830.1	SOX-TCF_HMG-box	141..212	CDD:238684	62/70 (89%)
sox-3	NP_510439.1	SOX-TCF_HMG-box	47..118	CDD:238684	62/70 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.850